Volume 124, Issue 7, Pages (June 2003)

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Volume 124, Issue 7, Pages 1792-1801 (June 2003) Nutritional supplementation with branched-chain amino acids in advanced cirrhosis: a double-blind, randomized trial Giulio Marchesini, Giampaolo Bianchi, Manuela Merli, Piero Amodio, Carmine Panella, Carmela Loguercio, Fillipo Rossi Fanelli, Roberto Abbiati Gastroenterology Volume 124, Issue 7, Pages 1792-1801 (June 2003) DOI: 10.1016/S0016-5085(03)00323-8

Figure 1 Kaplan-Meier analysis of event-free rates in cirrhosis supplemented with BCAA, L-ALB, or M-DXT. Events were considered death (any reason) and deterioration to exclusion criteria. The 4 patients who developed hepatocellular carcinoma were censored at the time of diagnosis. Gastroenterology 2003 124, 1792-1801DOI: (10.1016/S0016-5085(03)00323-8)

Figure 2 Albumin concentration, bilirubin levels, and Child-Pugh score in subjects supplemented with BCAA (closed bars), L-ALB (open bars), or M-DXT (dashed bars) who completed the 1-year study. Data are represented as means and 95% confidence intervals of the mean. The P values of time × treatment ANOVA are reported. Gastroenterology 2003 124, 1792-1801DOI: (10.1016/S0016-5085(03)00323-8)

Figure 3 Likert scale of hunger/anorexia (in centimeters) and role limitation/physical of the SF-36 questionnaire of health-related quality of life (in % maximum health) in subjects supplemented with BCAA (closed bars), L-ALB (open bars), or M-DXT (dashed bars) who completed the 1-year study. Data are represented as means and 95% confidence intervals of the mean. The P values of time × treatment ANOVA are reported. Gastroenterology 2003 124, 1792-1801DOI: (10.1016/S0016-5085(03)00323-8)