“Vitamin hypothesis”: explanation for allergy increase?

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Presentation transcript:

“Vitamin hypothesis”: explanation for allergy increase? by Stephan C. Bischoff Blood Volume 112(9):3535-3536 November 1, 2008 ©2008 by American Society of Hematology

The “vitamin hypothesis The “vitamin hypothesis.” Local production of RA by basophils at sites of allergic inflammation could enhance Th2 gene-expression programs as well as the phenotype and functions of T cells, B cells, and mast cells, supporting the concept that RA acts as a m... The “vitamin hypothesis.” Local production of RA by basophils at sites of allergic inflammation could enhance Th2 gene-expression programs as well as the phenotype and functions of T cells, B cells, and mast cells, supporting the concept that RA acts as a mediator of mucosal allergy. Stephan C. Bischoff Blood 2008;112:3535-3536 ©2008 by American Society of Hematology