ANTIMICROBIAL STEWARDSHIP PROGRAME

WHAT IS THE PROBLEM ? Attractiveness of new antibiotics to physicians Exaggerated claims by pharmaceutical industry After introduction of AB to medicine in 1940’s Cuurent situation in USA,60% OF HOSPITALIZED patients receive atleast one dose of AB (50% unnecessery)

UNWANTED CONSEQUENCE OF ANTIMICROBIAL THERAPY Adverse reaction Increased length of stay Increased cost of hospitalization 30%-50% of drug budget Predisposition to secondary infections Emergence of drug resistance microorganism Unique aspect which affects on other patients

FACTORS LEAD TO INAPPROPRIATE USE OF ANTIBIOTICS Good intention Inappropriate dosing Inappropriate prophylaxis Pressure from the patients Time constraints Independency to paraclinic results Inadequate knowledge about infectious disease Malpractice considerations “spiraling empiricism” Heavy promotion by drug companies

WHAT SHOULD WE DO ? Educational programs Microbial antibiogram updates Treatment updates Prophylaxis updates Interventional programs Treatment protocols Medical surgical Prophylaxis protocols Surgical Antimicrobial formulary restrictions