Chapter 12: Chromosome 12 12 A Cell Nucleus 12q24.31 66 aa Chromosome Name of Protein Chromosome Haemophilus influenzae type b and nontypeable strains. DNA Sequence 12 Name of Gene 12q24.31 HPD transcription Amino acid sequence mRNA 66 aa translation Cytoplasm What does this protein make up or do? A Cell Nucleus It serves as a vaccine Condition/Disease Tyrosinemia

Tyrosinemia Symptoms and characteristics Who is affected? Researcher: Enlargement of the liver and spleen are prominent Vomiting and diarrhea occur frequently Cirrhosis The abdomen is distended with fluid Weight gain If a baby doesn’t have a liver transport and it is needed they could die Who is affected? 1 out of 100,000 people Children mostly Researcher: LP

References http://www.genecards.org/cgi-bin/carddisp.pl?gene=HPD http://ghr.nlm.nih.gov/condition=tyrosinemia http://www.liver.ca/liver-disease/types/tyrosinemia.aspx http://omim.org/entry/609695 http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3209133/