2018 AG Coffee Shop 3.21.18 Dan Stein Review of the 2018 (FT–AI) Synchronization Protocols and Resources available to the Producer 2018 AG Coffee Shop 3.21.18 Dan Stein

At the beginning of the Breeding Season, most cow herds will consist of a mixture of: Non-cycling (anestrous) cows (heifers)… and Cycling cows (heifers)…

Role of Progesterone and GnRH in Initiating normal Estrous Cycles in anestrous Cows: Administration of GnRH (7 days) before treatment with PGF2α has been shown to increase estrus and ovulation rate in anestrous cows… Induction rate appears to be highest when cows receive a combination of Progestin and GnRH… (Stevenson et al., 2003) Many synchronization protocols will include the use of Progesterone and GnRH…

The ability to induce ovulation in anestrous primiparous cows was limited (< 20%) when BCS was less than 5. Smith, Pohler, Perry and Patterson, 2011

dinoprost tromethamine Prostaglandin dinoprost tromethamine 22 5cc Lutalyse ProstaMate Lutalyse HiCon In-Synch 22 2cc Federal (USA) law restricts this drug to use by or on the order of a licensed veterinarian

Prostaglandin cloprostenol sodium 2cc Estrumate Synchsure™ estroPLAN 22 2cc Estrumate Synchsure™ estroPLAN Federal (USA) law restricts this drug to use by or on the order of a licensed veterinarian

GnRH 2cc 1cc Cystorelin Fertagyl Ovacyst Factrel GONAbreed 22 22 2cc 1cc GONAbreed is approved by FDA for use in combination with Cloprostenol Sodium… FACTREL is approved by FDA for use in combination with Dinoprost Tromethamine... Federal (USA) law restricts this drug to use by or on the order of a licensed veterinarian

Progestins CIDR MGA Eazi-Breed (TM) – (single use) (0.5 mg/head/day) MGA should be fed at the same time period every day… …can have break-through’s (split and feed 2X/day)… T- Shaped (3 Parts) Nylon Spine – provides rigidity for retention Silicone Coat – contains 1.38 g progesterone Nylon tail for ease of removal

Can I afford to FT-AI? The ability to induce ovulation in anestrous primiparous cows was limited (< 20%) when BCS was less than 5… GnRH $2.74 CIDR $14.20 PG $2.77 Semen $25.00 Total $47.45 The time listed for “Fixed-time AI” should be considered as the approximate average time of insemination based on the number of cows to inseminate, labor, and facilities…

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*D.J. Drake et al. 2011 2 to 5 bulls/cow to bull ratio ~25:1 Can I afford to FT-AI? Hd./year Hd./4 yr. lifetime Calves produced a year in multi-sire pasture* 18 ± 5 72 Cost of a high accuracy bull** - sale average $3,800.00 Cost of 7-day protocol + semen $47.75 Number of cows that can be bred FT-AI per cost of bull** ($3,800.00 ÷ $47.75) 79 Number of calves to FT-AI (65% Pregnancy Rate) 51 *D.J. Drake et al. 2011 2 to 5 bulls/cow to bull ratio ~25:1 (semen = $25.00)

*D.J. Drake et al. 2011 2 to 5 bulls/cow to bull ratio ~25:1 Can I afford to FT-AI? Hd./year Hd./4 yr. lifetime Calves produced a year in multi-sire pasture* 18 ± 5 72 Cost of a high accuracy bull** - sale average $3,800.00 Cost of 7-day protocol + semen $47.75 Number of cows that can be bred FT-AI per cost of bull** ($3,800.00 ÷ $37.75) (semen = $15.00) 100 Number of calves to FT-AI (65% Pregnancy Rate) 65 *D.J. Drake et al. 2011 2 to 5 bulls/cow to bull ratio ~25:1

Questions ?