Laboratory of Information Technology Modeling the yield of chromosomal abberations at different post-irradiation times JINR Laboratory of Information Technology Wojciech Bizoń, Jagiellonian University, Cracow Supervisor: Joanna Deperas-Standyło

Chromosomal abberations Cell nucleus exposed for irradiation – damage in DNA 2. Abberations due to mistakes during self-repair process We can see abberations only when chromosomes are in mitosis (we can see a specific structure of chromosomes).

Monte Carlo modeling Hits per cell – Poisson Distribution 2. Propability that cell is in mithosis 3. Simulation (in Wolfram Mathematica 8.0)

Results Fitted to data after 48h Fitted to data after 72h/84h C-ions, 9.5MeV, 2Gy Fe-ions, 177MeV, 1.1Gy Fitted to data after 48h C-ions, 9.5MeV, 2Gy Fe-ions, 177MeV, 1.1Gy Fe-ions, 177MeV, 2.2Gy Fitted to data after 72h/84h

Thanks for attention!