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Nat. Rev. Neurol. doi:10.1038/nrneurol.2017.63 Figure 2 Hazard ratio and incidence rate ratio from five studies of dementia incidence Figure 2 | Hazard ratio and incidence rate ratio from five studies of dementia incidence. Reported figures are the ratios of the incidence estimate in new cohorts to that in old cohorts. If incidence estimates remain the same across two cohorts, the ratio is 1.0. If estimates are higher in new cohorts than old cohorts, the ratio is greater than 1.0. Estimates are adjusted as follows: Rotterdam study, IIDP and Bordeaux study adjusted for age; Framingham Heart Study adjusted for age and sex; CFAS adjusted for age, sex, area and deprivation. In the Bordeaux study, clinical diagnosis was made by neuropsychologists and neurologists using criteria from the Diagnostic and Statistical Manual III revised and V, and algorithmic diagnosis was based on cognitive and functional ability tests. CFAS, Cognitive Function and Ageing Study; IIDP, Indianapolis–Ibadan Dementia Project. Wu, Y.-T. et al. (2017) The changing prevalence and incidence of dementia over time — current evidence Nat. Rev. Neurol. doi:10.1038/nrneurol.2017.63