Issue Highlights Clinical Gastroenterology and Hepatology

Slides:



Advertisements
Similar presentations
Risk of Neoplasia After Colectomy in Patients With Inflammatory Bowel Disease: A Systematic Review and Meta-analysis Lauranne A.A.P. Derikx, Loes H.C.
Advertisements

A Panel to Predict Long-term Outcome of Infliximab Therapy for Patients With Ulcerative Colitis  Maria Theresa Arias, Niels Vande Casteele, Séverine Vermeire,
The Role of Psychosocial Care in Adapting to Health Care Reform
Withdrawal of Immunomodulators After Co-treatment Does Not Reduce Trough Level of Infliximab in Patients With Crohn’s Disease  David Drobne, Peter Bossuyt,
Abnormal Liver Tests and Fatty Liver on Ultrasound
Thrombocytopenia With Abnormal Liver Function Tests
Withdrawal of Immunomodulators After Co-treatment Does Not Reduce Trough Level of Infliximab in Patients With Crohn’s Disease  David Drobne, Peter Bossuyt,
Glomus Tumor of the Stomach—A Tumor That Needs to Be Differentiated From Gastrointestinal Stromal Tumor  Shuisheng Zhang, Jianwei Zhang, Chengfeng Wang 
Millie D. Long, Bruce E. Sands 
Efficacy of Topical 5-Aminosalicylates in Preventing Relapse of Quiescent Ulcerative Colitis: A Meta-analysis  Alexander C. Ford, Khurram J. Khan, William.
Adalimumab and Infliximab Are Equally Effective for Crohn's Disease in Patients Not Previously Treated With Anti–Tumor Necrosis Factor-α Agents  Christine.
Gauree Gupta, Ebbing Lautenbach, James D. Lewis 
A Shocking Cystory Clinical Gastroenterology and Hepatology
A Panel to Predict Long-term Outcome of Infliximab Therapy for Patients With Ulcerative Colitis  Maria Theresa Arias, Niels Vande Casteele, Séverine Vermeire,
Fernando Velayos, Uma Mahadevan 
Right Upper Quadrant Pain and a Normal Abdominal Ultrasound
Pushing the Pedal to the Metal: Should We Accelerate Infliximab Therapy for Patients With Severe Ulcerative Colitis?  Hans H. Herfarth, MD, PhD  Clinical.
Risk of Lymphoma Associated With Combination Anti–Tumor Necrosis Factor and Immunomodulator Therapy for the Treatment of Crohn's Disease: A Meta-Analysis 
A 31-Year-Old Patient With Colitis and Perianal Disease
Stephen A. Harrison, MD, FACP  Clinical Gastroenterology and Hepatology 
Levels of C-reactive Protein Are Associated With Response to Infliximab Therapy in Patients With Crohn's Disease  Matthias Jürgens, Jestinah M. Mahachie.
Andree Koop, Michael J. Bartel, Dawn Francis 
Talya Salz, Robert S. Sandler  Clinical Gastroenterology and Hepatology 
Association of Trough Serum Infliximab to Clinical Outcome After Scheduled Maintenance Treatment for Crohn’s Disease  Elana A. Maser, Renata Villela,
Perforation Risk Associated With Percutaneous Endoscopic Gastrostomy–Jejunal Tube Feeding in Pancreatic Walled Off Necrosis  Bronte A. Holt, Shyam Varadarajulu 
Jessica L. Mellinger, Michael L. Volk 
Issue Highlights Clinical Gastroenterology and Hepatology
Endoscopic Therapy for Barrett's Esophagus
Millie D. Long, Hans H. Herfarth, Clare A. Pipkin, Carol Q
Issue Highlights Clinical Gastroenterology and Hepatology
Abnormal Liver Tests and Fatty Liver on Ultrasound
Gastroenterology in a New Era of Accountability: Part 2
New Models of Gastroenterology Practice
Issue Highlights Clinical Gastroenterology and Hepatology
Issue Highlights Clinical Gastroenterology and Hepatology
David H. Bruining, William J. Sandborn 
Peter Bytzer  Clinical Gastroenterology and Hepatology 
Patient-Reported Outcomes of Cirrhosis
A Young Woman With Gallstone Pancreatitis and Abnormal Liver Tests: When Is Endoscopic Retrograde Cholangiopancreatography Needed?  Andrew D. Rhim, Michael.
Mucosal Healing Is Associated With Improved Long-term Outcomes of Patients With Ulcerative Colitis: A Systematic Review and Meta-analysis  Shailja C.
Issue Highlights Clinical Gastroenterology and Hepatology
Association Between Pharmacokinetics of Adalimumab and Mucosal Healing in Patients With Inflammatory Bowel Diseases  Xavier Roblin, Hubert Marotte, Melanie.
Early Trough Levels and Antibodies to Infliximab Predict Safety and Success of Reinitiation of Infliximab Therapy  Filip Baert, David Drobne, Ann Gils,
Tamir Ben–Menachem, Jason A. Dominitz 
Effects of Different Coping Strategies on Physical and Mental Health of Patients With Irritable Bowel Syndrome  Lilian Dindo, PhD  Clinical Gastroenterology.
Issue Highlights Clinical Gastroenterology and Hepatology
Alan Bonder, MD, Nezam H. Afdhal, MD 
John Scott Maul, Randall W. Burt, Lisa A. Cannon–Albright 
Thrombocytopenia With Abnormal Liver Function Tests
Issue Highlights Clinical Gastroenterology and Hepatology
Walter Reinisch, Jean-Frederic Colombel, William J
Predictors of Early Treatment Discontinuation Among Patients With Genotype 1 Hepatitis C and Implications for Viral Eradication  Lauren A. Beste, George.
Issue Highlights Clinical Gastroenterology and Hepatology
A 27-Year-Old Woman With Constipation: Diagnosis and Treatment
Patrick Yachimski, William P. Puricelli, Norman S. Nishioka 
Coagulation in Liver Disease: A Guide for the Clinician
Issue Highlights Clinical Gastroenterology and Hepatology
Hairball in the Stomach: A Case of Gastric Trichobezoar
Issue Highlights Clinical Gastroenterology and Hepatology
Risk of Pancreatitis in Patients With Celiac Disease: Is Autoimmune Pancreatitis a Biologically Plausible Mechanism?  John S. Leeds, David S. Sanders 
Issue Highlights Clinical Gastroenterology and Hepatology
Rintaro Hashimoto, Akimichi Chonan 
Adverse Outcomes: Why Bad Things Happen to Good People
Medical Therapy for Refractory Pediatric Crohn’s Disease
Issue Highlights Clinical Gastroenterology and Hepatology
Issue Highlights Clinical Gastroenterology and Hepatology
Rintaro Hashimoto, Akimichi Chonan 
The Role of Psychosocial Care in Adapting to Health Care Reform
Combination Therapy With Infliximab and Azathioprine Improves Infliximab Pharmacokinetic Features and Efficacy: A Post Hoc Analysis  Jean-Frédéric Colombel,
Choosing Wisely and the Perceived Drivers of Endoscopy Use
Presentation transcript:

Issue Highlights Clinical Gastroenterology and Hepatology Stephen B. Hanauer  Clinical Gastroenterology and Hepatology  Volume 13, Issue 3, Pages 413-415 (March 2015) DOI: 10.1016/j.cgh.2015.01.004 Copyright © 2015 AGA Institute Terms and Conditions

Figure 3 Predictive role of risk panel. Relapse and colectomy rate based on a risk panel including 5 independent risk factors, namely absence of short-term complete clinical response, absence of short-term mucosal healing, pANCA positivity, baseline albumin level less than 35 g/L, and baseline CRP level greater than 5 mg/L: (A) time to relapse, (B) time to colectomy, (C) clinical relapse rate within 12 months, and (D) colectomy rate within 60 months. Clinical Gastroenterology and Hepatology 2015 13, 413-415DOI: (10.1016/j.cgh.2015.01.004) Copyright © 2015 AGA Institute Terms and Conditions

Figure 4 Proposed algorithm for discontinuation of immunomodulator (IMM) in patients with durable response under combination treatment. ADA, adalimumab; IFX, infliximab; TL, trough level; TNF, tumor necrosis factor. Clinical Gastroenterology and Hepatology 2015 13, 413-415DOI: (10.1016/j.cgh.2015.01.004) Copyright © 2015 AGA Institute Terms and Conditions