Development and Validation of an Inflammatory Bowel Diseases Monitoring Index for Use With Mobile Health Technologies Welmoed K. Van Deen, Andrea E.

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Presentation transcript:

Development and Validation of an Inflammatory Bowel Diseases Monitoring Index for Use With Mobile Health Technologies Welmoed K. Van Deen, Andrea E. van der Meulen-de Jong, Nimisha K. Parekh, Ellen Kane, Aria Zand, Courtney A. DiNicola, Laurin Hall, Elizabeth K. Inserra, Jennifer M. Choi, Christina Y. Ha, Eric Esrailian, Martijn G.H. van Oijen, Daniel W. Hommes Clinical Gastroenterology and Hepatology Volume 14, Issue 12, Pages 1742-1750.e7 (December 2016) DOI: 10.1016/j.cgh.2015.10.035 Copyright © 2016 AGA Institute Terms and Conditions

Figure 1 Inclusion flowcharts for development phase (A) and validation phase (B). Clinical Gastroenterology and Hepatology 2016 14, 1742-1750.e7DOI: (10.1016/j.cgh.2015.10.035) Copyright © 2016 AGA Institute Terms and Conditions

Figure 2 Performance of the developed mHI scores to detect disease activity in CD (A–C) and UC (D–F). ROC curves of the mHI to predict clinical and endoscopic disease activity (A and D), scatter plot of the mHI versus clinical disease activity scores (B and E), and endoscopic disease activity scores (C and F). Clinical Gastroenterology and Hepatology 2016 14, 1742-1750.e7DOI: (10.1016/j.cgh.2015.10.035) Copyright © 2016 AGA Institute Terms and Conditions

Figure 3 Sensitivity to change (A and C) and test-retest reliability (C and D) of the mHI-CD (A and B) and mHI-UC (C and D). Clinical Gastroenterology and Hepatology 2016 14, 1742-1750.e7DOI: (10.1016/j.cgh.2015.10.035) Copyright © 2016 AGA Institute Terms and Conditions

Supplementary Figure 1 Seven-day diary form, which was sent to patients to log symptoms during the 7 days before the clinic visit for calculation of the CDAI. Clinical Gastroenterology and Hepatology 2016 14, 1742-1750.e7DOI: (10.1016/j.cgh.2015.10.035) Copyright © 2016 AGA Institute Terms and Conditions

Supplementary Figure 2 Screenshots of the mHI as implemented in the UCLA eIBD patient app available to patients treated at the UCLA IBD Center. Clinical Gastroenterology and Hepatology 2016 14, 1742-1750.e7DOI: (10.1016/j.cgh.2015.10.035) Copyright © 2016 AGA Institute Terms and Conditions