Urinary, Plasma, and Serum Biomarkers’ Utility for Predicting Acute Kidney Injury Associated With Cardiac Surgery in Adults: A Meta-analysis Julie Ho,

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Presentation transcript:

Urinary, Plasma, and Serum Biomarkers’ Utility for Predicting Acute Kidney Injury Associated With Cardiac Surgery in Adults: A Meta-analysis Julie Ho, MD, Navdeep Tangri, MD, PhD, Paul Komenda, MD, Amit Kaushal, MD, Manish Sood, MD, Ranveer Brar, BSc, Kamal Gill, BSc, Simon Walker, BSc, Kerry MacDonald, MLIS, Brett M. Hiebert, MSc, Rakesh C. Arora, MD, Claudio Rigatto, MD, MSc American Journal of Kidney Diseases Volume 66, Issue 6, Pages 993-1005 (December 2015) DOI: 10.1053/j.ajkd.2015.06.018 Copyright © 2015 The Authors Terms and Conditions

Figure 1 Selection of articles for review. Abbreviation: AKI, acute kidney injury. American Journal of Kidney Diseases 2015 66, 993-1005DOI: (10.1053/j.ajkd.2015.06.018) Copyright © 2015 The Authors Terms and Conditions

Figure 2 Forest plot of individual and composite areas under the receiver operating characteristic (ROC) curve (AUROCs) for all postoperative urinary biomarkers with more than 3 included studies. Abbreviations: CI, confidence interval; GST, glutathione S-transferase; IL, interleukin; KIM, kidney injury molecule; L-FABP, liver-type fatty acid binding protein; NAG, N-acetyl-β-d-glucosaminidase; NGAL, neutrophil gelatinase-associated lipocalin; u-, urinary. American Journal of Kidney Diseases 2015 66, 993-1005DOI: (10.1053/j.ajkd.2015.06.018) Copyright © 2015 The Authors Terms and Conditions

Figure 3 Forest plot of individual and composite areas under the receiver operating characteristic (ROC) curve (AUROCs) for all postoperative plasma or serum biomarkers with more than 3 included studies. Abbreviations: CI, confidence interval; NGAL, neutrophil gelatinase-associated lipocalin; p-, plasma. American Journal of Kidney Diseases 2015 66, 993-1005DOI: (10.1053/j.ajkd.2015.06.018) Copyright © 2015 The Authors Terms and Conditions