Bauer E. Sumpio, MD, PhD, Rachael O. Forsythe, MBChB, MRCS, Kenneth R

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Clinical implications of the angiosome model in peripheral vascular disease  Bauer E. Sumpio, MD, PhD, Rachael O. Forsythe, MBChB, MRCS, Kenneth R. Ziegler, MD, Jeff G. van Baal, MD, PhD, Mauri J.A. Lepantalo, MD, PhD, Robert J. Hinchliffe, MD, FRCS  Journal of Vascular Surgery  Volume 58, Issue 3, Pages 814-826 (September 2013) DOI: 10.1016/j.jvs.2013.06.056 Copyright © 2013 Society for Vascular Surgery Terms and Conditions

Fig 1 The foot and ankle area are divided into six angiosomes, with one angiosome fed by the anterior tibial artery (ATA), three by the posterior tibial artery (PTA), and two by the peroneal artery (PA). The ATA gives rise to the dorsalis pedis artery, supplying the anterior compartment and dorsum of the foot (pink). The PTA gives rise to the calcaneal branch, supplying the medial ankle (black) and plantar heel (green); the medial plantar branch, supplying the medial instep (yellow); and the lateral plantar branch, supplying the lateral and plantar forefoot (blue). The PA supplies the lateral ankle and plantar heel (red and green overlap) via the lateral calcaneal artery, and the anterior ankle via its anterior perforator (pink overlap). Note the overlap of the heel by both the medial calcaneal branch of the PTA and the lateral calcaneal branch of the PA. Journal of Vascular Surgery 2013 58, 814-826DOI: (10.1016/j.jvs.2013.06.056) Copyright © 2013 Society for Vascular Surgery Terms and Conditions

Fig 2 Summary of the article selection process. Journal of Vascular Surgery 2013 58, 814-826DOI: (10.1016/j.jvs.2013.06.056) Copyright © 2013 Society for Vascular Surgery Terms and Conditions

Fig 3 Quantitative assessment of local perfusion using indocyanine green (ICG) fluorescence imaging (Photodynamic Eye, Hamamatsu, Japan). Measurements are made from the video sequence with maximum intensity: A, Measurements 1 day before and 1 day after bypass from femoral to distal anterior tibial artery and amputation of 4th and 5th toes. B, Measurements 1 day before and 1 day after multilevel PTA on superficial femoral and popliteal artery as well on tibioperonel trunk and peroneal artery. PTA, Percutaneous transluminal angioplasty; PDE10, fluorescence intensity at 10 seconds from the rising point of the intensity curve, measurements from selected spots of interest (with tcpO2 measurements as reference); T½, time to reach the half of the maximum fluorescence intensity. Journal of Vascular Surgery 2013 58, 814-826DOI: (10.1016/j.jvs.2013.06.056) Copyright © 2013 Society for Vascular Surgery Terms and Conditions

Fig 4 Assessment of plantar angiosome perfusion utilizing hyperspectral imaging. The visual, integrated oxyhemoglobin-deoxyhemoglobin, and only deoxyhemoglobin hyperspectral images are shown of the plantar metatarsal angiosome for a foot with no PAD (left) and a foot with PAD (right). The foot with PAD demonstrates substantially decreased oxyhemoglobin and deoxyhemoglobin values throughout the angiosome. (Images courtesy of Jason Chin and Melina Kibbe.) PAD, Peripheral arterial disease. Journal of Vascular Surgery 2013 58, 814-826DOI: (10.1016/j.jvs.2013.06.056) Copyright © 2013 Society for Vascular Surgery Terms and Conditions