Rachelina P. Bartlett, M. D. , Philip R. Greipp, M. D

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Presentation transcript:

Extramedullary Hematopoiesis Manifesting as a Symptomatic Pleural Effusion Rachelina P. Bartlett, M.D., Philip R. Greipp, M.D., Ayalew Tefferi, M.D., Roger E. Cupps, M.D., Brian P. Mullan, M.D., Victor F. Trastek, M.D. Mayo Clinic Proceedings Volume 70, Issue 12, Pages 1161-1164 (December 1995) DOI: 10.4065/70.12.1161 Copyright © 1995 Mayo Foundation for Medical Education and Research Terms and Conditions

Fig. 1 Chest roentgenogram of 61-year-old woman, showing pronounced left-sided pleural effusion. Mayo Clinic Proceedings 1995 70, 1161-1164DOI: (10.4065/70.12.1161) Copyright © 1995 Mayo Foundation for Medical Education and Research Terms and Conditions

Fig. 2 Wright-stained pleural fluid smear, demonstrating immature granulocytes. (Original magnification, x250.) Mayo Clinic Proceedings 1995 70, 1161-1164DOI: (10.4065/70.12.1161) Copyright © 1995 Mayo Foundation for Medical Education and Research Terms and Conditions

Fig. 3 Biopsy specimen of bone marrow, showing cellular phase of agnogenic myeloid metaplasia and lack of acute leukemic transformation. (Hematoxylin-eosin; original magnification, x128.) Mayo Clinic Proceedings 1995 70, 1161-1164DOI: (10.4065/70.12.1161) Copyright © 1995 Mayo Foundation for Medical Education and Research Terms and Conditions

Fig. 4 Computed tomographic scan of chest, demonstrating leftsided infiltrate and pleural-based mass. Mayo Clinic Proceedings 1995 70, 1161-1164DOI: (10.4065/70.12.1161) Copyright © 1995 Mayo Foundation for Medical Education and Research Terms and Conditions

Fig. 5 99mTc scan, demonstrating increased uptake throughout thoracic cavity. Mayo Clinic Proceedings 1995 70, 1161-1164DOI: (10.4065/70.12.1161) Copyright © 1995 Mayo Foundation for Medical Education and Research Terms and Conditions

Fig. 6 Repeated posterior 99mTc scan, showing decreased left-sided uptake after radiation therapy. Mayo Clinic Proceedings 1995 70, 1161-1164DOI: (10.4065/70.12.1161) Copyright © 1995 Mayo Foundation for Medical Education and Research Terms and Conditions