Comparison of a multiplexed bead-based assay with an immunofluorescence and an enzyme-immuno assay for the assessment of Epstein–Barr virus serologic.

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Presentation transcript:

Comparison of a multiplexed bead-based assay with an immunofluorescence and an enzyme-immuno assay for the assessment of Epstein–Barr virus serologic status O. Devanthéry, P. Meylan Clinical Microbiology and Infection Volume 16, Issue 12, Pages 1776-1782 (December 2010) DOI: 10.1111/j.1469-0691.2010.03204.x Copyright © 2010 European Society of Clinical Infectious Diseases Terms and Conditions

FIG. 1 For each antibody type, the three methods were compared with each other. The lower left (negative) and upper right (positive) quadrants contain concordant data with the corresponding number of sera shown. The upper left and lower right quadrants show discordant data. Numbers of data shown in the grey zone correspond to sera with minor discrepancies. Anti-viral capsid antigen IgM were determined at a single 1: 10 dilution in the immunofluorescence assay. Samples were arbitrarily assigned a 1 : 5 titre if negative and 1 : 20 if positive. BBA, bead-based assay; EBNA, Epstein–Barr nuclear antigen; EIA, enzyme immunoassay; IF, immunofluorescence; VCA, viral capsid antigen. Clinical Microbiology and Infection 2010 16, 1776-1782DOI: (10.1111/j.1469-0691.2010.03204.x) Copyright © 2010 European Society of Clinical Infectious Diseases Terms and Conditions