Volume 70, Issue 4, Pages (May 2011)

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Volume 70, Issue 4, Pages 597-613 (May 2011) Translating Stem Cell Studies to the Clinic for CNS Repair: Current State of the Art and the Need for a Rosetta Stone Karen Aboody, Alexandra Capela, Nilofar Niazi, Jeffrey H. Stern, Sally Temple Neuron Volume 70, Issue 4, Pages 597-613 (May 2011) DOI: 10.1016/j.neuron.2011.05.007 Copyright © 2011 Elsevier Inc. Terms and Conditions

Figure 1 The Pipeline from Bench to Bedside: Costs Estimated at $1 Billion over Ten Years Neuron 2011 70, 597-613DOI: (10.1016/j.neuron.2011.05.007) Copyright © 2011 Elsevier Inc. Terms and Conditions

Figure 2 Drug Development Process Analysis 1Liu (2010). 2DiMasi (2001). 3PricewaterhouseCoopers (2008). Neuron 2011 70, 597-613DOI: (10.1016/j.neuron.2011.05.007) Copyright © 2011 Elsevier Inc. Terms and Conditions

Figure 3 Bench-to-Bedside Translation of Stem Cell Therapies to CNS Clinical Trials Regulatory information for clinical trials. Neuron 2011 70, 597-613DOI: (10.1016/j.neuron.2011.05.007) Copyright © 2011 Elsevier Inc. Terms and Conditions

Figure 4 Stem Cell-Mediated CNS Regeneration and Therapeutic Delivery Schematic identifying representative CNS stem cell replacement, regeneration, and therapeutic delivery strategies. Neuron 2011 70, 597-613DOI: (10.1016/j.neuron.2011.05.007) Copyright © 2011 Elsevier Inc. Terms and Conditions