Volume 66, Issue 5, Pages (November 2004)

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Date of download: 6/29/2016 Copyright © The American College of Cardiology. All rights reserved. From: The metabolic syndrome, diabetes, and subclinicalatherosclerosis.

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Presentation transcript:

Volume 66, Issue 5, Pages 2022-2031 (November 2004) Determinants of coronary artery calcification in diabetics with and without nephropathy Rajnish Mehrotra, Matthew Budoff, Peter Christenson, E.L.I. Ipp, Junichiro Takasu, Ajay Gupta, Keith Norris, Sharon Adler Kidney International Volume 66, Issue 5, Pages 2022-2031 (November 2004) DOI: 10.1111/j.1523-1755.2004.00974.x Copyright © 2004 International Society of Nephrology Terms and Conditions

Figure 1 Box-plots comparing the coronary artery calcification score among diabetic controls and those with diabetic nephropathy. The bold line reflects the median score, the upper and lower lines of the box represent the 25th and 75th percentile for the category, and lines represent the extreme values for the coronary artery calcification score. The coronary artery calcification score of controls (N = 30, score: 4 and 0 and 125, median, 25th and 75th percentile, respectively) was significantly lower than among individuals with diabetic nephropathy (N = 60, score: 66 and 8 and 393, median, 25th and 75th percentile, respectively) (P < 0.001). Kidney International 2004 66, 2022-2031DOI: (10.1111/j.1523-1755.2004.00974.x) Copyright © 2004 International Society of Nephrology Terms and Conditions

Figure 2 (A and B) Scatter plots comparing the CAC scores among individuals with DN and controls to the 25th, 50th, 75th, and 90th percentile scores from 8673 nondiabetic individuals (5945 men and 2728 women) between the ages of 40 and 65 years, with non-evidence of manifest CAD, and who have undergone EBCT scanning at Harbor-UCLA Medical Center. The closed circles represent the individuals with DN, and the open circles represent the diabetic controls. Individuals with DN were significantly more likely to have scores greater than the 50th percentile (82% vs. 57%, P = 0.01) or the 90th percentile (32% vs. 7%, P = 0.008) for age and gender, when compared to diabetic controls. Kidney International 2004 66, 2022-2031DOI: (10.1111/j.1523-1755.2004.00974.x) Copyright © 2004 International Society of Nephrology Terms and Conditions