Umbilical cord blood transplantation and cytomegalovirus: posttransplantation infection and donor screening by Maria S. Albano, Patricia Taylor, Robert.

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Presentation transcript:

Umbilical cord blood transplantation and cytomegalovirus: posttransplantation infection and donor screening by Maria S. Albano, Patricia Taylor, Robert F. Pass, Andromachi Scaradavou, Rodica Ciubotariu, Carmelita Carrier, Ludy Dobrila, Pablo Rubinstein, and Cladd E. Stevens Blood Volume 108(13):4275-4282 December 15, 2006 ©2006 by American Society of Hematology

Schematic representation of case-control studies 1 and 2, respectively. Schematic representation of case-control studies 1 and 2, respectively. (A) Case-control study 1: detection of CMV infection by saliva culture and confirmation by polymerase chain reaction (PCR). (B) Case-control study 2: detection of possible CMV infection by PCR in saliva culture–negative infants. Maria S. Albano et al. Blood 2006;108:4275-4282 ©2006 by American Society of Hematology

Incidence of CMV infection after transplantation. Incidence of CMV infection after transplantation. Cumulative incidence of posttransplantation CMV infection in recipients who were CMV-antibody negative or unevaluable (A) or CMV-antibody positive (B) before transplantation: relationship to the cord blood donor's maternal anti-CMV antibody status. Relative risk (RR) and significance (P) were estimated by Cox regression. Maria S. Albano et al. Blood 2006;108:4275-4282 ©2006 by American Society of Hematology