Risk of Acute Liver Failure in Patients With Drug-Induced Liver Injury: Evaluation of Hy’s Law and a New Prognostic Model Vincent Lo Re, Kevin Haynes,

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Risk of Acute Liver Failure in Patients With Drug-Induced Liver Injury: Evaluation of Hy’s Law and a New Prognostic Model Vincent Lo Re, Kevin Haynes, Kimberly A. Forde, David S. Goldberg, James D. Lewis, Dena M. Carbonari, Kimberly B.F. Leidl, K. Rajender Reddy, Melissa S. Nezamzadeh, Jason Roy, Daohang Sha, Amy R. Marks, Jolanda De Boer, Jennifer L. Schneider, Brian L. Strom, Douglas A. Corley Clinical Gastroenterology and Hepatology Volume 13, Issue 13, Pages 2360-2368 (December 2015) DOI: 10.1016/j.cgh.2015.06.020 Copyright © 2015 AGA Institute Terms and Conditions

Figure 1 Selection of patients in the study. anti-HBc, hepatitis B core antibody; anti-HCV, hepatitis C virus antibody; anti-HDV, hepatitis D virus antibody; HBeAg, hepatitis B e antigen; HBsAg, hepatitis B surface antigen; HBV, hepatitis B virus; HCV, hepatitis C virus; HDV, hepatitis D virus; IgM, immunoglobulin. *ICD-9 codes 573.3 or 573.8. †Index date = first qualifying date of drug-induced liver injury. ‡Patients may have had more than 1 exclusionary diagnosis recorded. §The upper limits of normal of alanine and aspartate aminotransferase were determined by the assay from which each result was measured. Clinical Gastroenterology and Hepatology 2015 13, 2360-2368DOI: (10.1016/j.cgh.2015.06.020) Copyright © 2015 AGA Institute Terms and Conditions