Three years of specific immunotherapy may be sufficient in house dust mite respiratory allergy Ana I. Tabar, MD, PhD, Esozia Arroabarren, MD, Susana.

Slides:

Advertisements

Similar presentations

Joint modeling of parentally reported and physician-confirmed wheeze identifies children with persistent troublesome wheezing Danielle C.M. Belgrave, MSc,

Advertisements

A bioinformatics approach to identify patients with symptomatic peanut allergy using peptide microarray immunoassay Jing Lin, PhD, Francesca M. Bruni,

Control of immunopathology during chikungunya virus infection Caroline Petitdemange, PhD, Nadia Wauquier, PhD, Vincent Vieillard, PhD Journal of Allergy.

Defective B-cell memory in patients with Down syndrome Ruud H.J. Verstegen, MD, Gertjan J. Driessen, MD, Sophinus J.W. Bartol, BSc, Carel J.M. van Noesel,

Reducing relative humidity to control the house dust mite Dermatophagoides farinae Larry G. Arlian, PhD, Jacqueline S. Neal, BS, DiAnn L. Vyszenski-Moher,

Endoplasmic reticulum stress influences bronchial asthma pathogenesis by modulating nuclear factor κB activation So Ri Kim, MD, PhD, Dong Im Kim, MS, Mi.

Peter Vadas, MD, PhD, Boris Perelman, PhD, Gary Liss, MD, MS

Home Environmental Interventions for the Prevention or Control of Allergic and Respiratory Diseases: What Really Works Pierre Le Cann, PhD, Hélène Paulus,

Jonathan A. Bernstein, MD, David M. Lang, MD, David A. Khan, MD

Allergen immunotherapy: A practice parameter third update

Pharmacologic rationale for treating allergic and nonallergic rhinitis

Clarification concerning amoxicillin skin testing

Quoting a landmark paper on the beneficial effects of probiotics

Fatty acids, inflammation, and asthma

Santa Jeremy Ono, BA, PhD, Mark B. Abelson, MD

Allergen vaccination with a liposome-encapsulated extract of Dermatophagoides pteronyssinus : A randomized, double-blind, placebo-controlled trial in.

Evaluation of BCG administration as an adjuvant to specific immunotherapy in asthmatic children with mite allergy Andrea Cohon, MD, L. Karla Arruda,

Is 9 more than 2 also in allergic airway inflammation?

Desensitization to Chemotherapeutic Agents

Jonathan A. Bernstein, MD, David M. Lang, MD, David A. Khan, MD

Fatty acids, inflammation, and asthma

Allergy immunotherapy among Medicaid-enrolled children with allergic rhinitis: Patterns of care, resource use, and costs Cheryl S. Hankin, PhD, Linda.

An Infant with Atopic Dermatitis and Itching After Ingestion of Milk

Lieuwe D. Bos, MSc, PhD, Peter J. Sterk, MD, PhD, Stephen J

Clinical studies of the DP1 antagonist laropiprant in asthma and allergic rhinitis George Philip, MD, Janet van Adelsberg, MD, Thomas Loeys, PhD, Nancy.

Dust mite ingestion–associated, exercise-induced anaphylaxis

Physician needs in health informatics: Just ask the docs

Simultaneous detection of total and allergen-specific IgE by using purified allergens in a fluorescent multiplex array Eva-Maria King, PhD, Lisa D. Vailes,

Peter M. Wolfgram, MD, David B. Allen, MD

William J. Calhoun, MD, Tmirah Haselkorn, PhD, Dave P

Successful management of mite-allergic asthma with modified extracts of Dermatophagoides pteronyssinus and Dermatophagoides farinae in a double-blind,

Jewlya Lynn, PhD, Sophie Oppenheimer, MS, MPH, Lorena Zimmer, MA

Reply Journal of Allergy and Clinical Immunology

Debra J. Palmer, PhD, Thomas R. Sullivan, BMa&CompSc(Hons), Michael S

Phillip Lieberman, MD, Michael Tankersley, MD

Time for a paradigm shift in asthma treatment: From relieving bronchospasm to controlling systemic inflammation Leif Bjermer, MD Journal of Allergy.

Tolerated wasp sting challenge improves health-related quality of life in patients allergic to wasp venom Jörg Fischer, MD, Martin Teufel, MD, Alexandra.

Phillip Lieberman, MD, David Golden, MD

Food allergy: A review and update on epidemiology, pathogenesis, diagnosis, prevention, and management Scott H. Sicherer, MD, Hugh A. Sampson, MD Journal.

Biosimilars and drug development in allergic and immunologic diseases

Daphne Koinis-Mitchell, PhD, Timothy Craig, DO, Cynthia A

A cluster-randomized trial shows telephone peer coaching for parents reduces children's asthma morbidity Jane M. Garbutt, MB, ChB, Yan Yan, MD, PhD,

Peter Vadas, MD, PhD, Boris Perelman, PhD, Gary Liss, MD, MS

Update on the role of prostaglandins in allergic lung inflammation: Separating friends from foes, harder than you might think Martin L. Moore, PhD, R.

Sharon Seth, MD, David A. Khan, MD

What is an “eosinophilic phenotype” of asthma?

Autophagy: Nobel Prize 2016 and allergy and asthma research

Higher incidence of pediatric anaphylaxis in northern areas of the United States William J. Sheehan, MD, Dionne Graham, PhD, Lin Ma, MS, Sachin Baxi,

Food allergy: Epidemiology, pathogenesis, diagnosis, and treatment

Advances in the approach to the patient with food allergy

House dust mite sublingual immunotherapy: Results of a US trial

Geographic variability in childhood asthma prevalence in Chicago

High prevalence of severe asthma in a large random population study

Sublingual immunotherapy in mite-sensitized children with atopic dermatitis: A randomized, double-blind, placebo-controlled study Giovanni B. Pajno,

Efficacy and safety of sublingual tablets of house dust mite allergen extracts in adults with allergic rhinitis Karl-Christian Bergmann, MD, Pascal Demoly,

Martin Brasholt, MD, Florent Baty, PhD, Hans Bisgaard, MD, DMSci

Eosinophilic esophagitis treated with immunotherapy to dust mites

Change in visual analog scale score in a pragmatic randomized cluster trial of allergic rhinitis Philippe-Jean Bousquet, MD, Christophe Combescure, PhD,

Measles and immunomodulation

Guus A. Westerhof, MD, Elise M. Vollema, MD, Els J

Macrolide antibiotics and asthma treatment

Statistical issues in clinical trials that involve the double-blind, placebo-controlled food challenge Vernon M. Chinchilli, PhD, Laura Fisher, MD, Timothy.

Asthma: The past, future, environment, and costs

Environmental factors and eosinophilic esophagitis

News & Notes Journal of Allergy and Clinical Immunology

Efficacy of a short course of specific immunotherapy in patients with allergic rhinoconjunctivitis to ragweed pollen Piyush Patel, MD, Tom Holdich, MBBS,

The GILL study: Glycerin-induced local reactions in immunotherapy

Double-blind, placebo-controlled study with a modified therapeutic vaccine of Salsola kali (Russian thistle) administered through use of a cluster schedule

Natural history of cow’s milk allergy

Primary prevention of asthma and allergy

Presentation transcript:

Three years of specific immunotherapy may be sufficient in house dust mite respiratory allergy Ana I. Tabar, MD, PhD, Esozia Arroabarren, MD, Susana Echechipía, MD, PhD, Blanca E. García, MD, PhD, Santiago Martin, MS, María J. Alvarez-Puebla, MD, PhD Journal of Allergy and Clinical Immunology Volume 127, Issue 1, Pages 57-63.e3 (January 2011) DOI: 10.1016/j.jaci.2010.10.025 Copyright © 2010 American Academy of Allergy, Asthma & Immunology Terms and Conditions

Fig 1 Study design. Arrows, Randomization. Red triangle, STOP immunotherapy. T0 to T1: results published in Tabar AI, Echechipía S, García BE, Olaguibel JM, Lizaso MT, Gómez B, et al. Double-blind comparative study of cluster and conventional immunotherapy schedules with Dermatophagoides pteronyssinus. J Allergy Clin Immunol 2005;116:109-18. Journal of Allergy and Clinical Immunology 2011 127, 57-63.e3DOI: (10.1016/j.jaci.2010.10.025) Copyright © 2010 American Academy of Allergy, Asthma & Immunology Terms and Conditions

Fig 2 Patients’ flowchart throughout the study. Journal of Allergy and Clinical Immunology 2011 127, 57-63.e3DOI: (10.1016/j.jaci.2010.10.025) Copyright © 2010 American Academy of Allergy, Asthma & Immunology Terms and Conditions

Fig 3 A, Rhinitis severity (global score). B, Asthma severity (global score). C, VAS score. Mean values (black line) (SEs).∗P < .001. CO, Control group. Journal of Allergy and Clinical Immunology 2011 127, 57-63.e3DOI: (10.1016/j.jaci.2010.10.025) Copyright © 2010 American Academy of Allergy, Asthma & Immunology Terms and Conditions

Fig 4 RQLQ and AQLQ scores. A, IT5. B, IT3. C, Control group. Mean values (black line) (SEs). ∗P < .01. Journal of Allergy and Clinical Immunology 2011 127, 57-63.e3DOI: (10.1016/j.jaci.2010.10.025) Copyright © 2010 American Academy of Allergy, Asthma & Immunology Terms and Conditions