C.-L. Wu, K. Kimmerling, D. Little, F. Guilak

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Serum free fatty acid levels as predictors of the severity of obesity-associated osteoarthritis C.-L. Wu, K. Kimmerling, D. Little, F. Guilak Osteoarthritis and Cartilage Volume 24, Pages S58-S59 (April 2016) DOI: 10.1016/j.joca.2016.01.128 Copyright © 2016 Terms and Conditions

Fig 1 Serum levels of (A) SFAs (B) MUFAs (C) ω-6 PUFAs, and (D) ω-3 PUFAs for the mice fed various diets. One-way ANOVA with Tukey's HSD post-hoc analysis for each FA. EPA: eicosapentaenoic acid. DHA: docosahexaenoic acid. Different letters are significantly different from each other (p < 0.05). Mean±SEM. Osteoarthritis and Cartilage 2016 24, S58-S59DOI: (10.1016/j.joca.2016.01.128) Copyright © 2016 Terms and Conditions

Fig 2 Three highest concentrations of synovial FAs were presented for each FA category. Synovial fluid levels of (A) SFAs (B) MUFAs (C) ω-6 PUFAs, and (D) ω-3 PUFAs for the right non-operated joints (R), and the left DMM-operated joints (DMM) of the mice fed various diets. EPA: eicosapentaenoic acid. DHA: docosahexaenoic acid. Repeated measures ANOVA using right joints as the contralateral control for each FA. # p < 0.05 compared to its own counterpart in the right non-operated joints. Mean±SEM. Osteoarthritis and Cartilage 2016 24, S58-S59DOI: (10.1016/j.joca.2016.01.128) Copyright © 2016 Terms and Conditions

Fig. 3 Correlations of serum (A) stearic acid (B) palmitoleic acid (C) linoleic acid, and (D) EPA with OA severity of the DMM-operated joints. Serum palmitoleic acid and EPA were negatively correlated with OA severity. EPA: eicosapentaenoic acid. *p < 0.05, **p < 0.01.5 Osteoarthritis and Cartilage 2016 24, S58-S59DOI: (10.1016/j.joca.2016.01.128) Copyright © 2016 Terms and Conditions