Multiple Myeloma: Interleukin-15 Antagonizes Bone Morphogenetic Protein-Induced Apoptosis and Growth Inhibition. by Magne Rekvig, Anne-Tove Brenne, Torstein.

Slides:



Advertisements
Similar presentations
BMP3: To Be or Not To Be a BMP by Matthew E. Bahamonde, and Karen M Lyons J Bone Joint Surg Am Volume 83(1 suppl 1):S56-S62 March 1, 2001 ©2001 by The.
Advertisements

Lymphoma dissemination: the other face of lymphocyte homing by Steven T. Pals, David J. J. de Gorter, and Marcel Spaargaren Blood Volume 110(9):
Clinical regressions and broad immune activation following combination therapy targeting human NKT cells in myeloma by Joshua Richter, Natalia Neparidze,
Farnesyltransferase inhibitor tipifarnib is well tolerated, induces stabilization of disease, and inhibits farnesylation and oncogenic/tumor survival pathways.
Generating AML-Specific Peripheral Blood Autologous Cytotoxic T-Lymphocytes (CTLs)‏ by Rohtesh S. Mehta, Xiaohua Chen, Antony Jeyaraj, and Paul Szabolcs.
Inhibition of NF-κB induces apoptosis of KSHV-infected primary effusion lymphoma cells by Shannon A. Keller, Elaine J. Schattner, and Ethel Cesarman Blood.
Green tea polyphenols block the anticancer effects of bortezomib and other boronic acid–based proteasome inhibitors by Encouse B. Golden, Philip Y. Lam,
Targeting the p27 E3 ligase SCF Skp2 results in p27- and Skp2-mediated cell-cycle arrest and activation of autophagy by Qing Chen, Weilin Xie, Deborah.
The Prognostic Value Of Dynamic Monitoring C-Reactive Protein (CRP) Serum Levels In NK/T-Cell Lymphoma by Bing Bai, Qi-chun Cai, Xiao-Xiao Wang, Qingqing.
Figure 3 Energy metabolism regulation, cardiovascular and bone disease in CKD Figure 3 | Energy metabolism regulation, cardiovascular and bone disease.
Pocket-sized iron regulators: one size fits all?
Combination of 4Ts score and PF4/H-PaGIA for diagnosis and management of heparin-induced thrombocytopenia: prospective cohort study by Lori-Ann Linkins,
Autologous stem cell transplantation followed by a dose-reduced allograft induces high complete remission rate in multiple myeloma by Nicolaus Kröger,
Positioning NK-κB in multiple myeloma
Insulin-like growth factor binding protein-3 antagonizes the effects of retinoids in myeloid leukemia cells by Takayuki Ikezoe, Sakae Tanosaki, Utz Krug,
An endothelial metronome breast cancer?
Retroviral and Chemical Mutagenesis Identifies Pax5 as a Tumor Suppressor in B-Progenitor Acute Lymphoblastic Leukemia by Jinjun Dang, Charles G Mullighan,
A Clinical Evaluation of the International Lymphoma Study Group Classification of Non-Hodgkin's Lymphoma Blood Volume 89(11): June 1, 1997 ©1997.
by Nataliya Melnyk, and Jonathan Harrison
T-cell epitopes within the complementarity-determining and framework regions of the tumor-derived immunoglobulin heavy chain in multiple myeloma by Lotta.
BTK inhibition in myeloma: targeting the seed and the soil
The Hematopoietic Stem Cell Transplant Comorbidity Index (HCT-CI) Can Predict for Readmission Following Autologous Stem Cell Transplant for Lymphoma and.
Transplants for the elderly in myeloma
How I treat elderly patients with myeloma
Validation of the Nordic Scoring System for Erythropoietic Stimulating Agents in MDS Using IWG 2006 Erythroid Response Criteria by Jennifer Jayakar, Richard.
Elevated Plasma Von Willebrand Factor and Decreased ADAMTS13 Antigen Levels in Patients with Immune Thrombocytopenia (ITP)‏ by Charlotte Louise Godfrey,
Nonmyeloablative conditioning for relapsed follicular lymphoma
Symptomatic and Incidental Venous Thromboembolic Disease Are Both Associated With Mortality In Patients With Prostate Cancer by Shruti Chaturvedi, Surbhi.
Mechanisms of HIV-associated lymphocyte apoptosis
Interleukin-3 (IL-3) is overexpressed by T lymphocytes in multiple myeloma patients by Nicola Giuliani, Francesca Morandi, Sara Tagliaferri, Simona Colla,
The role of complete response in multiple myeloma
by Petri Salven, Lasse Teerenhovi, and Heikki Joensuu
An Unusual Cause of Abdominal Pain in Sickle Cell Disease
Genetic sequence analysis of inherited bleeding diseases
by Jonathan N. Hofmann, Linda M. Liao, Michael N
Protease inhibitors potentiate chemotherapy-induced neutropenia
by John C. Wood, Pinggao Zhang, Hugh Y
Suppression, surprise: galectin-10 and Treg cells
Solitary plasmacytoma of bone and asymptomatic multiple myeloma
Taking a leaf from the book of oral tolerance
Has the T cell bitten off more than it can chew?
Interleukin-21 is a growth and survival factor for human myeloma cells
Incidence, clinical course, and prognosis of secondary monoclonal gammopathy of undetermined significance in patients with multiple myeloma by Rishi K.
Discovery of Unique Biomarkers That Predict Bortezomib-Induced Peripheral Neuropathy: The Results of a Multicenter Prospective Clinical Study of Multiple.
by Douglas D. Ross, Judith E. Karp, Tar T. Chen, and L. Austin Doyle
Biomarkers in kidney fibrosis: are they useful?
Lymphoma spread? Target CD47-SIRPα!
Bone Turnover Biomarkers Are Useful In Monitoring Myeloma Bone Disease and As Early Predictor Biomarkers For Relapse Disease In Multiple Myeloma by Kay.
HU for acute treatment of sickle VOC?
Yang et al. SALL4 is a key regulator of survival and apoptosis in human leukemic cells. Blood. 2008;112(3):805–813. Blood Volume 114(14): October.
Bone morphogenetic protein-2 induces apoptosis in human myeloma cells with modulation of STAT3 by Chiharu Kawamura, Masahiro Kizaki, Kenji Yamato, Hideo.
Activity of eltrombopag in severe aplastic anemia
Pathophysiology of Bone Metastases in Prostate Cancer
by Achille Iolascon, Hermann Heimpel, Anders Wahlin, and Hannah Tamary
by Santosh L. Saraf, Xu Zhang, Tamir Kanias, James P. Lash, Robert E
Dichotomous Role of Interferon-γ in Allogeneic Bone Marrow Transplant
by Fumiko Chino, Arif H. Kamal, Junzo Chino, and Thomas W. LeBlanc
Erratum in Ledru et al. Alteration of tumor necrosis factor–α T-cell homeostasis following potent antiretroviral therapy: contribution to the development.
Schematic model of the mechanism of Tak1 protection of HSPC survival.
PRIMA-1Met inhibits the growth of multiple myeloma tumors with mutant p53 in vivo. PRIMA-1Met inhibits the growth of multiple myeloma tumors with mutant.
Rituximab immunotherapy: it’s getting personal
Mesenchymal Stem Cell-Derived Vesicles Reverse Hematopoietic Radiation Damage by Sicheng Wen, Laura R Goldberg, Mark S Dooner, John L Reagan, and Peter.
Representative staining of bone marrow aspirates collected from a patient at baseline and after 1 cycle of treatment with 45 mg/m2 selinexor + 20 mg dexamethasone,
Pure red cell aplasia by Robert T. Means Blood
Hepatosplenic T-Cell Lymphoma: Clinicopathological Features and Treatment Outcomes: Report From The North American Peripheral T-Cell Lymphoma Consortium.
by Holbrook E Kohrt, Idit Sagiv-Barfi, Sarwish Rafiq, Sarah E. M
by Dana S. Levy, Jason A. Kahana, and Rakesh Kumar
Patient Tregs express normal levels of suppression.
Effect of IS on proliferation, senescence, and the production of NO and ROS from endothelial cells. Effect of IS on proliferation, senescence, and the.
Cold agglutinin disease
Presentation transcript:

Multiple Myeloma: Interleukin-15 Antagonizes Bone Morphogenetic Protein-Induced Apoptosis and Growth Inhibition. by Magne Rekvig, Anne-Tove Brenne, Torstein Baade Ro, Anders Waage, Magne Borset, and Anders Sundan Blood Volume 108(11):3444-3444 November 16, 2006 ©2006 by American Society of Hematology

Proliferation in response to BMP-4 stimulus. Magne Rekvig et al. Blood 2006;108:3444 ©2006 by American Society of Hematology

Apoptosis in response to BMP-4 stimulus. Magne Rekvig et al. Blood 2006;108:3444 ©2006 by American Society of Hematology