Fay Kastrinos, Elena M. Stoffel

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Presentation transcript:

History, Genetics, and Strategies for Cancer Prevention in Lynch Syndrome Fay Kastrinos, Elena M. Stoffel Clinical Gastroenterology and Hepatology Volume 12, Issue 5, Pages 715-727 (May 2014) DOI: 10.1016/j.cgh.2013.06.031 Copyright © 2014 AGA Institute Terms and Conditions

Figure 1 MSS, microsatellite stable. §PREMM1,2,6 score can be calculated at http://premm.dfci.harvard.edu/. ¶Other models (MMRpro, MMRpredict) may also be used with their own specified cut-off scores. *BRAF testing: (+), mutation present; (−), mutation absent/wild type. **Surveillance recommendations based on personal and family history. ‡Gene-specific germline mutational analysis. Clinical Gastroenterology and Hepatology 2014 12, 715-727DOI: (10.1016/j.cgh.2013.06.031) Copyright © 2014 AGA Institute Terms and Conditions