Transcriptional Regulation

Slides:



Advertisements
Similar presentations
Regulation of Gene Expression
Advertisements

Gene regulation. Gene expression models  Prokaryotes and Eukaryotes employ common and different methods of gene regulation  Prokaryotic models 1. Trp.
Genetic Regulatory Mechanisms
OUTLINE 3 III.Control of Gene Expression in Prokaryotes A. Regulatory proteins B. The operon model C. Examples 1. the lac operon (substrate induction)
Copyright © 2005 Pearson Education, Inc. publishing as Benjamin Cummings Concept 18.4: Individual bacteria respond to environmental change by regulating.
To understand the concept of the gene function control. To understand the concept of the gene function control. To describe the operon model of prokaryotic.
Control of Prokaryotic Gene Expression. Prokaryotic Regulation of Genes Regulating Biochemical Pathway for Tryptophan Synthesis. 1.Produce something that.
AP Biology Chapter 18: Gene Regulation. Regulation of Gene Expression Important for cellular control and differentiation. Understanding “expression” is.
Regulation of gene expression References: 1.Stryer: “Biochemistry”, 5 th Ed. 2.Hames & Hooper: “Instant Notes in Biochemistry”, 2 nd Ed.
Operons. Big picture Prokaryotic control of genome expression Prokaryotic control of genome expression 2 levels of control 2 levels of control  Change.
Bacterial Operons A model of gene expression regulation Ch 18.4.
Chapter 16 Control of Gene Expression. Topics to discuss DNA binding proteins Prokaryotic gene regulation –negative inducible: lac operon –negative repressible:
Control of Gene Expression Big Idea 3: Living systems store, retrieve, transmit, and respond to info essential to life processes.
Differential Expression of Genes  Prokaryotes and eukaryotes precisely regulate gene expression in response to environmental conditions  In multicellular.
Gene Control Chapter 11. Prokaryotic Gene Regulation Operons, specific sets of clustered genes, are the controlling unit Promoter: sequence where RNA.
Control of gene expression Unit but different cells have different functions and look and act differently! WHY? Different sets of genes are expressed.
Draw 8 boxes on your paper
CONTROL MECHANISMS 5.5. Controlling Transcription and Translation of Genes  Housekeeping Genes: needed at all times: needed for life functions vital.
Gene Expression and Regulation
Regulation of gene expression in prokaryotes Katalin Kiss Dept. of Medical Biology
Bacterial Gene Expression and Regulation
For the following replication fork, which strand would be leading? 5’ Top Strand Bottom Strand.
Gene Regulation, Part 1 Lecture 15 Fall Metabolic Control in Bacteria Regulate enzymes already present –Feedback Inhibition –Fast response Control.
Chapter 16 – Control of Gene Expression in Prokaryotes
Section 2 CHAPTER 10. PROTEIN SYNTHESIS IN PROKARYOTES Both prokaryotic and eukaryotic cells are able to regulate which genes are expressed and which.
Gene Regulation Packet #46 Chapter #19.
Prokaryotic cells turn genes on and off by controlling transcription.
Bacteria Gene Regulation. Compare/Contrast Prokaryotic and Eukaryotic Protein Synthesis.
Copyright © 2008 Pearson Education Inc., publishing as Pearson Benjamin Cummings 18.1: The trp operon.
Eukaryotic Gene Regulation
Gene expression in prokaryotes. Operon system One promoter can regulate many genes ?What about eukaryotes.
Gene Expression & Regulation Chapter 8.6. KEY CONCEPT Gene expression is carefully regulated in both prokaryotic and eukaryotic cells.
Gene Expression Chapter 16. DNA regulatory sequence All on DNA Promoters – Start transcription Promoters – Start transcription Terminators – End Transcription.
Warm Up Write down 5 times it would be beneficial for a gene to be ‘turned off’ and the protein not be expressed 1.
Genetics of Bacteria Bacterial genome =.
The Lac Operon An inducible operon
OPERONS * Indicated slides borrowed from: Kim Foglia
Control of Gene Expression
Regulation of Gene Expression
Differential Expression of Genes
Lac Operon Lactose is a disaccharide used an energy source for bacteria when glucose is not available in environment Catabolism of lactose only takes place.
Goals today: Describe the parts of an operon
Control of Gene Expression
Chapter 16 Control of Gene Expression
Gene Regulation.
Prokaryotic cells turn genes on and off by controlling transcription.
Prokaryotic cells turn genes on and off by controlling transcription.
Regulation of Gene Expression
Daily Warm-Up Tuesday, Jan. 7th
Homework #2 is posted and due 10/17
Chapter 12.5 Gene Regulation.
The Operon Hypothesis The Operon Hypothesis was developed by 2 researchers: Jacob and Monod It explains how genes are regulated in prokaryotes. They received.
Regulation of Gene Expression
Prokaryotic cells turn genes on and off by controlling transcription.
Gene Regulation Packet #22.
Control of Prokaryotic (Bacterial) Genes Different from Eukaryotes!
Gene Expression Activation of a gene to transcribe DNA into RNA.
Prokaryotic cells turn genes on and off by controlling transcription.
Transcriptional Regulation in Prokaryotes.
Chapter 18 Bacterial Regulation of Gene Expression
Review Warm-Up What is the Central Dogma?
Objective 3: TSWBAT recognize the processes by which bacteria respond to environmental changes by regulating transcription.
Prokaryotic (Bacterial) Gene Regulation
Control of Prokaryotic (Bacterial) Genes
Prokaryotic cells turn genes on and off by controlling transcription.
Prokaryotic cells turn genes on and off by controlling transcription.
Gene Regulation A gene (DNA) is expressed when it is made into a functional product (protein/enzyme)
Prokaryotic cells turn genes on and off by controlling transcription.
Presentation transcript:

Transcriptional Regulation 1

2

Activators-bind enhancer elements Transcriptional Control—by Transcription Factors (DNA-binding proteins) Activators-bind enhancer elements Repressors-bind repressor elements (or ‘operator elements’, or ‘operators’ in bacteria) 3

Prokaryotic ‘Operons’ examples 4

Trp Operon-Biosynthesis -10 -35 5

6

7

Lac Operon-Catabolism 8

-35 -10 9

Lactose ON -35 -10 10

Lactose ON -35 -10 -10 -35 11

-35 -10 12

In the absence of glucose…. cAMP 13

-35 -10 14

ON 15

Eukaryotic Genes 16

-25 17

Combinatorial Control of Gene Expression 18

19

20

induced Pluripotent Stem cell 21

+ Feedback 22

Regulatory protein 1 Off

Gene Silencing 23

Feedback: Privacy Policy Feedback
Do Not Sell My Personal Information
About project: SlidePlayer Terms of Service

© 2025 SlidePlayer.com. Inc. All rights reserved.