The Aging Liver in the Aging HIV and HCV Patients

Slides:

Advertisements

Similar presentations

The Aging Liver in the Aging HIV Patient

Advertisements

Non Cirrhotic Portal Hypertension: A Serious Hepatic Complication in HIV and the Use of Transient Elastography for Diagnosis Dronamraju D,Vachon ML, and.

HBV and HIV HIV and HBV VG Naidoo Gastroenterology.

HCV cure: new treatment paradigms for HCV infection Sanjay Bhagani Consultant Physician/Senior Lecturer Royal Free Hospital/UCL London.

Dr. David Pearson Gastroenterology, Victoria.  None relevant to this presentation.

Hcv infection and management in advanced liver disease

BORDERNETwork Training on HIV and HBV Co-Infections Dr. med. Wolfgang Güthoff / Alexander Leffers, M.A.

The Progression of Liver Fibrosis is Associated with the Severity of the HIV Disease in HIV-HCV Co-infected Female Patients Mohammad K. Mohammad 1, Babu.

Protein GP73 (GOLGI PROTEIN 73) A NEW NON-INVASIVE BIOMARKER FOR ASSESSING LIVER FIBROSIS AND RISK OF PROGRESSION TO HEPATOCELLULAR CARCINOMA N.K. Gatselis,

Metabolic Factors / NAFLD on the Natural History of Chronic Hepatitis B or C in Asia Pei-Jer Chen National Taiwan University & Hospital.

ADAP ADVOCACY ASSOCIATION 2013 HIV/HCV CO-INFECTION ADAP SUMMIT ROBERT L. CALDWELL, PH.D. A MEDICAL PERSPECTIVE ON HIV/HCV CO- INFECTION HIV and Hepatitis.

Impact of weight management in chronic HCV Egyptian patients on liver fibrosis. By: Dr. Osama A. Fekry Lecturer of CN at the AUC Head of clinical Nutrition.

Renal Transplantation for HIV/HCV Co-infected Patients Solid Organ Transplantation and People With HIV: Ethics and Policy Conference David Oldach & Robert.

Liver fibrosis regression after anti HCV therapy and the rate of death, liver-related death, liver- related complications, and hospital.

FT in prognostic of HBV FibroTest: predictive value in HBV.

Hepatitis C+ Recipients: Considerations for Exclusion Emily A. Blumberg, M.D.

HBV related complications in HIV positive patients during HAART therapy Irina Magdalena Dumitru*, E. Dumitru*, S. Rugina*, Roxana Carmen Cernat**, Simona.

Role of HIV-1 Nef in Acceleration of HCV-Mediated Liver Disease 1.

Liver transplantation for HCV infection R3 양 인 호 /Prof 김 병 호.

Problems of HIV Infection in the HAART Era Akihiko Suganuma M.D. Tokyo Metropolitan Komagome Hospital Department of Infectious Diseases.

Setting the Scene. Non A, non B Hepatitis  Early 1970’s recognised that 2/3 of post transfusional hepatitis were –ve for both Hep A & Hep B Non Hep A.

HBV. Overview of the Epidemiology of Hepatotropic Viruses.

Date of download: 9/17/2016 From: The Changing Burden of Hepatitis C Virus Infection in the United States: Model-Based Predictions Ann Intern Med. 2014;161(3):

Hepatitis C Consultation Services (844) | 9AM-5PM ET, M-F nccc.ucsf.edu The Clinician Consultation Center (CCC) provides up-to-date expert clinical.

HIV and Hepatitis C Co-Infection

Abstract MOAB0301 Hepatitis C Care Cascade for People Living With HIV in the Country of Georgia Nikoloz Chkhartishvili1, A. Abutidze1, N. Bolokadze1, O.

National Hepatitis C Database

Lesson 2: Special Considerations When Treating HIV/HCV Co-infection

Volume 67, Issue 3, Pages (September 2017)

Long-term impact of response to interferon-based therapy in patients with chronic HCV in relation to liver function, survival and cause of death Philip.

HCV & liver transplantation

Figure 1. Prevalence of undocumented hepatitis C virus (HCV) infection, by age, race, and sex in 4713 emergency department patients, From: Evaluation.

Sofosbuvir plus Peg-Interferon and Ribavirin in Treatment Experienced Patients with Hepatitis C Virus and HIV Co-Infection Mehri Nikbin, MD Infectious.

A. Stepanov, A. Kruk, N. Polovinkina, A. Vinogradova

Clinical outcome after SVR: Veterans Affairs

DOES HIV/ HEPATITIS COINFECTION AFFECT PEOPLE ACCESSING CARE FOR HIV

Volume 143, Issue 4, Pages e14 (October 2012)

HIV/HCV Co-Infection Case

Non-alcoholic steatohepatitis with positive ANA

HCV. The Spectrum of Hepatitis C Virus Infection: From Acute Infection to End-Stage Liver Disease.

The prevalence of alcohol-induced liver disease and hepatitis C and their interaction in a tertiary care setting Adnan Said, John Williams, Jeremy Holden,

World Epidemiology. Are HIV and Other Chronic Diseases Models Applicable to Viral Hepatitis? Focus on HCV.

Coinfection With HIV-1 and HCV—A One-Two Punch

Les Lang Gastroenterology Volume 133, Issue 1, (July 2007)

More Than Treatment.

Les Lang Gastroenterology Volume 133, Issue 1, (July 2007)

Phase 3 Treatment Naïve HIV Coinfection

Evaluation of the Patient With HCV Infection

Alcoholic hepatitis with diffuse interstitial fibrosis

Hepatitis C in the HIV-infected patient

ARV-trial.com IMPACT Study: SMV + DCV + SOF in HCV genotype 1 with decompensated liver disease Design Open label ≥ 18 years Chronic HCV infection Genotype.

The prevalence of alcohol-induced liver disease and hepatitis C and their interaction in a tertiary care setting Adnan Said, John Williams, Jeremy Holden,

Figure 1 Proposed algorithm for the management

Care of the Treatment-naive Patient With HCV/HIV Coinfection

Thomas F. Baumert, Catherine Fauvelle, Diana Y. Chen, Georg M. Lauer

Clinical outcome after SVR: ANRS CO22 HEPATHER

I. Carmona, P. Cordero, J. Ampuero, A. Rojas, M. Romero-Gómez

Impact of metabolic risk factors on HCC

Trends in the management and burden of alcoholic liver disease

Volume 141, Issue 4, Pages e3 (October 2011)

REAL-WORLD SAFETY, EFFECTIVENESS, AND PATIENT-REPORTED OUTCOMES IN PATIENTS WITH CHRONIC HEPATITIS C VIRUS INFECTION TREATED WITH GLECAPREVIR/PIBRENTASVIR:

Coinfection With HIV-1 and HCV—A One-Two Punch

Factors related to the chronicity and evolution of hepatitis C infection in patients co- infected by the human immunodeficiency virus R. Pérez-Cano, C.

Volume 67, Issue 3, Pages (September 2017)

Non-invasive evaluation of liver fibrosis using transient elastography

Core Competency 1: Epidemiologic Background of HIV/HCV Co-infection in the United States Lesson 2: Morbidity and Mortality in HCV Co-infected People Living.

Managing Hepatitis C in Vermont

Effect of Hepatitis C Eradication on Markers of Macrophage Activation and Microbial Translocation in HIV Seropositive Women Kerianne Burke1, Elizabeth.

Presentation transcript:

The Aging Liver in the Aging HIV and HCV Patients

The HIV-Infected Population is Aging

Persons Living with HIV/AIDS in USA CDC Surveillance Program

HIV Results in Accelerated Age-related Conditions

Change in Causes of Death in Persons with HIV Reflects Aging

Change in Causes of Death in Patients with HIV Reflects Aging

HCV Status Strongly Influences Causes of Death in HIV-Infected Patients

Aging, HIV and the Immune System: Interactions

HIV and Microbial Translocation

Microbial Translocation in HIV

Early Immune Senescence in HIV Disease

Aging, HIV and the liver: Interactions

Aging, HIV and the liver: Interactions

Chronic Elevation of Liver Enzymes in HIV

Chronic Elevation of Liver Enzymes in HIV

The HIV Aging Liver and Steatosis

Drug-Induced Liver Injury

HCC in HIV-Infected Patients

Age and HCC in HIV-Infected Patients

HCC in HIV-Infected Patients

Age and HCC in HIV-Infected Patients

Non Cirrhotic Portal Hypertension: Long-Term Liver Complication of ART

Aging and HIV also Impact HCV

Early Immunosenescence with HCV?

HCV-Infected Persons Are Aging

HCV-Related Cirrhosis prevalence Is Projected to Peak Over the Next 10 Years

Liver fibrosis is Accelerated in HIV/HCV Co-Infected Patients

Baseline Fibrosis Stage According to Age in HIV/HCV Co-Infection

HIV-related Microbial Translocation and Progression of Hepatitis C

Role of Microbial translocation in liver fibrosis?

HIV-related Gut CD4+ T cell Depletion and Microbial Translocation Contributes to HCV Progression

sCD14 on first 33 patients

Baseline Fibroscan Scores in HCV Mono-infected Patients

Baseline Fibroscan Scores in HIV/HCV Co-infected Patients

sCD14 Values of 7 Patients with Increasing FibroScan Scores Over 12 Months

HIV-related Microbial Translocation and Progression of Hepatitis C

Conclusions

Change in Causes of Death in Persons with HIV Reflects Aging

HCV Status Strongly Influences Causes of Death in HIV-Infected Patients

Early Immune Senescence in HIV Disease

Steatosis/Steatohepatitis Is an Emerging Cause of Liver Disease in HIV

Steatosis/Steatohepatitis Is an Emerging Cause of Liver Disease in HIV