Hoong-Yeet Yeang, PhD, Siti Arija M

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Presentation transcript:

Hev b 5 and Hev b 13 as allergen markers to estimate the allergenic potency of latex gloves  Hoong-Yeet Yeang, PhD, Siti Arija M. Arif, PhD, Monika Raulf-Heimsoth, PhD, Yin-Ho Loke, Ingrid Sander, PhD, Siti Hawa Sulong, MS, Chee-Heng Lau, PhD, Robert G. Hamilton, PhD  Journal of Allergy and Clinical Immunology  Volume 114, Issue 3, Pages 593-598 (September 2004) DOI: 10.1016/j.jaci.2004.05.039

Fig 1 Relationships between JHU IgE inhibition CAP (μg/g) and latex allergen contents (ng/g) in 24 glove eluates. The abscissa values are (A) Hev b 5 content, (B) Hev b 13 content, and (C) 0.576 (Hev b 5 content)+0.864 (Hev b 13 content) – 39.05. ∗∗P < .01. ∗∗∗P < .001. Journal of Allergy and Clinical Immunology 2004 114, 593-598DOI: (10.1016/j.jaci.2004.05.039)

Fig 2 Validation of the JHU allergen marker regression model using data from low-protein gloves and a different reference serum in the IgE inhibition measurements. Relationships between BGFA IgE inhibition CAP (μg/g) and latex allergen contents (ng/g) or total protein (μg/g) in eluates from 9 gloves with less than 200 μg/g protein are shown. The abscissa values are (A) 0.576 (Hev b 5 content)+0.864 (Hev b 13 content) – 39.05, and (B) total protein. ∗P < .05. ∗∗∗P < .001. Journal of Allergy and Clinical Immunology 2004 114, 593-598DOI: (10.1016/j.jaci.2004.05.039)