K. -M. Kaukonen, R. Linko, H. Herwald, L. Lindbom, E. Ruokonen, T

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Heparin-binding protein (HBP) in critically ill patients with influenza A (H1N1) infection  K.-M. Kaukonen, R. Linko, H. Herwald, L. Lindbom, E. Ruokonen, T. Ala-Kokko, V. Pettilä  Clinical Microbiology and Infection  Volume 19, Issue 12, Pages 1122-1128 (December 2013) DOI: 10.1111/1469-0691.12156 Copyright © 2013 European Society of Clinical Infectious Diseases Terms and Conditions

Fig. 1 Heparin binding protein (HBP) concentrations (ng/mL) at admission correlated with WBC (white blood cell) count (×109) at admission (rho = 0.444, p <0.01) but not with CRP (C-reactive protein, g/L) at admission (rho = 0.266, p 0.179). Clinical Microbiology and Infection 2013 19, 1122-1128DOI: (10.1111/1469-0691.12156) Copyright © 2013 European Society of Clinical Infectious Diseases Terms and Conditions

Fig. 2 Upper panel: HBP concentrations (ng/mL) in patients with and without invasive mechanical ventilation at baseline (p 0.088) and day 2 (p <0.01). Lower panel: HBP concentrations in tertiles of patients divided according to admission PF ratio at baseline and day 2 (p ns). Clinical Microbiology and Infection 2013 19, 1122-1128DOI: (10.1111/1469-0691.12156) Copyright © 2013 European Society of Clinical Infectious Diseases Terms and Conditions

Fig. 3 Heparin binding protein concentrations (ng/mL) at baseline and day 2 in patients with and without corticosteroid therapy (p not significant at baseline; p <0.05 at day 2) and with and without severe sepsis or septic shock during their ICU stay (p not significant at baseline and day 2). Clinical Microbiology and Infection 2013 19, 1122-1128DOI: (10.1111/1469-0691.12156) Copyright © 2013 European Society of Clinical Infectious Diseases Terms and Conditions