Microarray analysis each spot represents one gene Yellow: no change in gene expression Green: the gene is turned off in the tumor Red: the gene is turned on in the tumor

Analyzing Human Breast Cancer Types By Microarray Analysis

Identifying genes whose expression changes at specific stages of the cell cycle

Implications for sleep disorders day night day night day night Circadian Rhythms and Sleep Genes whose expression changes during the day in fruit flies (and people) Implications for sleep disorders

Arp3 Arp2 Arc40 Arc35 Arc19 Arc18 Arc15 Example from Bruce Goode,

Fig. 1. Representation of chromosome V incorporating genetic footprinting data. Each box is colored to summarize the results obtained to date from genetic footprinting. Mutant phenotypes: Q1, all selections, <75% population growth rate; Q2, all selections, 75 to 85% population growth rate; Q3, all selections, 85 to <100% population growth rate. Genes in which mutations gave distinctive phenotypes under specific selections are colored according to the selection(s) affected, as follows: M: (dark green),: minimal medium;. L (teal),: lactate medium;. H (orange),: high temperature;. C (brown),: caffeine;. S (yellow),: high salt;. X (light green),: mating;. WT (dark blue),: wild-type for all selections;. NR (grey)

bim1 x rad54