Ronald D. Emkey, MD, Mark Ettinger, MD

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Presentation transcript:

Improving Compliance and Persistence with Bisphosphonate Therapy for Osteoporosis Ronald D. Emkey, MD, Mark Ettinger, MD The American Journal of Medicine Volume 119, Issue 4, Pages S18-S24 (April 2006) DOI: 10.1016/j.amjmed.2005.12.019 Copyright © 2006 Elsevier Inc. Terms and Conditions

Figure 1 (A) Unrecognized vertebral fracture in women ≥60 years of age, hospitalized for various reasons (n=132 of 934). (B) Undertreatment of hip fracture for hospitalized patients (N=1,076) from 4 Midwestern hospitals. BP = blood pressure; DXA = dual X-ray absorptiometry. (Adapted from Osteoporos Int1 and Arthritis Rheum.2) The American Journal of Medicine 2006 119, S18-S24DOI: (10.1016/j.amjmed.2005.12.019) Copyright © 2006 Elsevier Inc. Terms and Conditions

Figure 2 Patients on existing bisphosphonate therapy who remained on therapy after 12 months. (Adapted from Arthritis Rheum.24) The American Journal of Medicine 2006 119, S18-S24DOI: (10.1016/j.amjmed.2005.12.019) Copyright © 2006 Elsevier Inc. Terms and Conditions

Figure 3 Changes in lumbar spine bone mineral density with daily risedronate (5 mg) and 2 formulations of once-weekly risedronate (35 mg and 50 mg). (Adapted from Calcif Tissue Int.28) The American Journal of Medicine 2006 119, S18-S24DOI: (10.1016/j.amjmed.2005.12.019) Copyright © 2006 Elsevier Inc. Terms and Conditions

Figure 4 Changes in lumbar spine bone mineral density (BMD) with daily ibandronate (2.5 mg) and 3 formulations of once-monthly ibandronate (50/50 mg, 100 mg, and 150 mg). ⁎P <0.001 vs daily regimen. (Adapted from “Once-monthly Oral Ibandronate Dosing Is Highly Efficacious in Postmenopausal Osteoporosis.”31) The American Journal of Medicine 2006 119, S18-S24DOI: (10.1016/j.amjmed.2005.12.019) Copyright © 2006 Elsevier Inc. Terms and Conditions