Volume 66, Issue 1, Pages 156-163 (July 2014) Prediction of 90-day Mortality After Radical Cystectomy for Bladder Cancer in a Prospective European Multicenter Cohort  Atiqullah Aziz, Matthias May, Maximilian Burger, Rein-Jüri Palisaar, Quoc-Dien Trinh, Hans-Martin Fritsche, Michael Rink, Felix Chun, Thomas Martini, Christian Bolenz, Roman Mayr, Armin Pycha, Philipp Nuhn, Christian Stief, Vladimir Novotny, Manfred Wirth, Christian Seitz, Joachim Noldus, Christian Gilfrich, Shahrokh F. Shariat, Sabine Brookman-May, Patrick J. Bastian, Stefan Denzinger, Michael Gierth, Florian Roghmann  European Urology  Volume 66, Issue 1, Pages 156-163 (July 2014) DOI: 10.1016/j.eururo.2013.12.018 Copyright © 2013 European Association of Urology Terms and Conditions

Fig. 1 Calibration plot of the Isbarn nomogram predicting 90-d mortality after radical cystectomy in the present cohort. Variables included age (≤60 vs 61–68, 69–83, 84–88, ≥89 yr), stage (regional vs localized), grade (1–2 vs 3–4), and histologic subtype (urothelial carcinoma vs squamous cell carcinoma, other). Abbreviations: Dxy=Somer's D rank correlation, R2=Nagelkerke-Cox-Snell-Maddala-Magee R-squared index, D=Discrimination index, U=Unreliability index, Q=Quality index, Emax=maximum absolute difference in predicted and calibrated propabilities, S:z=Spiegelhalter Z-test, S:p=two-tailed p-value of the Spiegelhalter Z-test. European Urology 2014 66, 156-163DOI: (10.1016/j.eururo.2013.12.018) Copyright © 2013 European Association of Urology Terms and Conditions

Fig. 2 Calibration plot of the newly developed preoperative nomogram predicting 90-d mortality after radical cystectomy. Abbreviations: Dxy=Somer's D rank correlation, R2=Nagelkerke-Cox-Snell-Maddala-Magee R-squared index, D=Discrimination index, U=Unreliability index, Q=Quality index, Emax=maximum absolute difference in predicted and calibrated propabilities, S:z=Spiegelhalter Z-Test, S:p=two-tailed p-value of the Spiegelhalter Z-test. European Urology 2014 66, 156-163DOI: (10.1016/j.eururo.2013.12.018) Copyright © 2013 European Association of Urology Terms and Conditions

Fig. 3 Preoperative nomogram predicting 90-d mortality after radical cystectomy. To obtain the nomogram-predicted probability of 90-d mortality, locate the patient values on each axis. Draw a vertical line to the “Points” axis to determine how many points are attributed for each variable value. Add the points of all variables. Locate the sum on the “Total Points” line to assess the individual probability of 90-d mortality. ASA=American Society of Anesthesiologists. European Urology 2014 66, 156-163DOI: (10.1016/j.eururo.2013.12.018) Copyright © 2013 European Association of Urology Terms and Conditions