Volume 60, Issue 1, Pages 106-117 (July 2011) The Controversial Relationship Between Benign Prostatic Hyperplasia and Prostate Cancer: The Role of Inflammation  Cosimo De Nunzio, Gero Kramer, Michael Marberger, Rodolfo Montironi, William Nelson, Fritz Schröder, Alessandro Sciarra, Andrea Tubaro  European Urology  Volume 60, Issue 1, Pages 106-117 (July 2011) DOI: 10.1016/j.eururo.2011.03.055 Copyright © 2011 European Association of Urology Terms and Conditions

Fig. 1 The distribution of inflammation, benign prostatic hyperplasia, proliferative inflammatory atrophy (PIA), high-grade intraepithelial neoplasia (HGPIN), and prostate cancer (PCa) in the human prostate: (A) a single slice of a prostate from a radical prostatectomy specimen, (B) a microscopic image (haematoxylin and eosin). (C) In a low-magnification microscopic image of the region indicated in (B) and a higher-magnification image of the different lesions observed, inflammation is shown by the red line and arrow, PIA by the white line and arrow, HGPIN by the green line and arrow, and PCa by the black line and arrow). BPH=benign prostatic hyperplasia; PCa=prostate cancer; HGPIN=high-grade intraepithelial neoplasia; PIA=proliferative inflammatory atrophy. European Urology 2011 60, 106-117DOI: (10.1016/j.eururo.2011.03.055) Copyright © 2011 European Association of Urology Terms and Conditions