Mortality HRs for dialysis modality (PD versus HD) in 23,718 incident dialysis patients using a marginal structural model (MSM) taking into account changes.

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Mortality HRs for dialysis modality (PD versus HD) in 23,718 incident dialysis patients using a marginal structural model (MSM) taking into account changes in dialysis modality and transplant censorship in the first 2 years (Supplemental Table 3). Mortality HRs for dialysis modality (PD versus HD) in 23,718 incident dialysis patients using a marginal structural model (MSM) taking into account changes in dialysis modality and transplant censorship in the first 2 years (Supplemental Table 3). Model 1, inverse probability weight (IPW): age, baseline modality, and time-dependent modality (TD; stabilized IPW mean=1.06); model 2, IPW: age, sex, race, DM, baseline modality, and TD (stabilized IPW mean=1.06); model 3, IPW: age, sex, race, DM, baseline modality (Alb and Hgb), and TD modality (Alb and Hgb; stabilized IPW mean=1.29); MSM adjustment 1, IPW-adjusted (IPWs were calculated using different sets of variables); MSM adjustment 2, IPW + adding the same variables used to calculate IPWs to control for residual confounding; MSM adjustment 3, same as MSM adjustment 2 + additional confounders: marital status, employment, baseline comorbidities (COPD, cancer, hypertension, ability to ambulate, heart failure, and atherosclerotic heart disease), and baseline serum levels of ferritin, calcium, phosphorus, and nPCR. Lilia R. Lukowsky et al. CJASN 2013;8:619-628 ©2013 by American Society of Nephrology