Sequence variation in the promoter region of the cholinergic receptor muscarinic 3 gene and asthma and atopy Joseph Donfack, PhDa, Paul Kogut, BSb, Sean.

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Presentation transcript:

Sequence variation in the promoter region of the cholinergic receptor muscarinic 3 gene and asthma and atopy Joseph Donfack, PhDa, Paul Kogut, BSb, Sean Forsythe, MDb, Julian Solway, MDb, Carole Ober, PhDa Journal of Allergy and Clinical Immunology Volume 111, Issue 3, Pages 527-532 (March 2003) DOI: 10.1067/mai.2003.71 Copyright © 2003 Mosby, Inc. Terms and Conditions

Fig. 1 The 1.2-kb promoter region of the CHRM3 gene. The promoter region was divided into 4 overlapping segments. Approximate positions of primer pairs are shown in the lower half of the figure. The SNPs and STRPs detected in this study are shown as circles and squares , respectively. The shaded segment represents 175 bp of the promoter segment that was not screened; −1 represents the first nucleotide upstream of the transcriptional start site of the CHRM3 gene.15 Journal of Allergy and Clinical Immunology 2003 111, 527-532DOI: (10.1067/mai.2003.71) Copyright © 2003 Mosby, Inc. Terms and Conditions