Equipoise ”Balance of forces or interests”

Clinical equipoise or the principle of equipoise provides the ethical basis for medical research that involves assigning patients to different treatment arms of a clinical trial. The term was first used by Benjamin Freedman in 1987. Freedman et al NEJM 1987

How is equipoise defined or interpreted How is equipoise defined or interpreted? Experiences of the individual physician or defined by the level of uncertainty that exists in the medical community Freedman et al NEJM 1987

REVIVE-IT RCT OMM versus LVAD Ambulatory, non-inotrope dependent cohort with advanced heart failure Receiving maximal medical therapy NYHA class III limitations LVEF < 35% 6 MWT distance < 300m Peak VO2 between 30 - 50% of predicted with an absolute value < 16 ml/Kg/min for men and < 14 ml/Kg/min for women

Speakers Ileana Pina, MD MPH Andrew Boyle, MD Larry Allen, MD