Quiz #7 (8%) Biol710 11/21/12 name___________

Slides:



Advertisements
Similar presentations
Lecture 8 Transcription Initiation Prokaryotic Eukaryotic Reading: Chapter 4 ( ) Chapter 11 Molecular Biology syllabus web siteweb site.
Advertisements

Copyright Pearson Prentice Hall
You start with a biologically relevant protein from a pathogen (Bacterium, virus, parasite…)
Name:_______________ Quiz 9: Biol 203 Fall 2013 Lab Instructor Name (1pt):_______________ 26pts total A HD R Arl E1E2E3 4pts. If they own only circle enhancers.
20,000 GENES IN HUMAN GENOME; WHAT WOULD HAPPEN IF ALL THESE GENES WERE EXPRESSED IN EVERY CELL IN YOUR BODY? WHAT WOULD HAPPEN IF THEY WERE EXPRESSED.
Regulating Gene Expression Turning Genes On and Off.
Protein-Protein Interaction Screens. Bacterial Two-Hybrid System selectable marker RNA polymerase DNA binding protein bait target sequence target.
MCB 7200: Molecular Biology
BSL2016 / 2018 – Lecture 7 – cDNA libraries cDNA synthesis results in the generation of 1000’s of cDNA molecules. All these cDNA molecules are derived.
Gene Regulation How does your body know when to make certain proteins? Unit 4 – Chapter 12-5.
Transcription Central Dogma Sense (codon) vs antisense (non-coding) Types of RNAs Structural genes vs regulatory genes RNA polymerases (I, II, III) Promoters.
Gene regulation. How does DNA make different cells? All cells have a full set of DNA Not all the DNA is expressed in each one Promoters and repressors.
Gene Regulation in Prokaryotes - plasmid, not protected by nuclear envelope - DNA is not bound up with histones -One of the best known pathways is the.
Transcription control elements (DNA sequences) are binding sites for transcription factors, proteins that regulate transcription from an associated.
Transcription … from DNA to RNA.
Prokaryotic cells turn genes on and off by controlling transcription.
Eukaryotic Gene Expression. The expression of genes found in DNA The expression of genes found in DNA The genes expressed in a particular cell determines.
Figure S1. Alignment of sequences from the 5′-end to the Sm binding site of reported genomic sequences (9-15) for HSUR 1. MicroRNA binding sites are.
DNA LIBRARIES Dr. E. What Are DNA Libraries? A DNA library is a collection of DNA fragments that have been cloned into a plasmid and the plasmid is transformed.
Protein-protein interactions Why study protein interactions? To infer function To understand regulatory networks Approach With given bait, discover target.
Genome Annotation Assessment in Drosophila melanogaster by Reese, M. G., et al. Summary by: Joe Reardon Swathi Appachi Max Masnick Summary of.
The two-hybrid system – why?
A Molecular Toolkit AP Biology Fall The Scissors: Restriction Enzymes  Bacteria possess restriction enzymes whose usual function is to cut apart.
Trends in Biotechnology Constructing and Screening a DNA Library.
Name:_______________ Quiz 9: Biol 203 Fall 2013 Lab Instructor Name (1pt):_______________ 26pts total A HD R Arl E1E2E3 4pts. Circle the portion of the.
Gene Expression & Regulation Chapter 8.6. KEY CONCEPT Gene expression is carefully regulated in both prokaryotic and eukaryotic cells.
HOW DO CELLS KNOW WHEN TO EXPRESS A GENE? DO NOW:.
REVIEW OF MOLECULAR GENETICS DR. EDELBERG. Genes, DNA, & Chromosomes.
Quiz#8 LC710 11/28/11 name___________
Alignment table: group 4
Control of Gene Expression
How does your body know when to make proteins?
How does your body know when to make proteins? Unit 4 – Chapter 12-5
Quiz #4(8%) Biol710 11/05/12 name___________
12-5 Gene Regulation Pages 309 – 312 Block 1 Baker.
Name:_______________
Fig. S Fig. S2 Cre-mediated recombination in vivo. G2 mice displaying high levels of GFP were crossed.
Control of Gene Expression
Prokaryotic cells turn genes on and off by controlling transcription.
Quiz #5 (9%) Biol710 11/7/12 name___________
Prokaryotic cells turn genes on and off by controlling transcription.
Chapter 12.5 Gene Regulation.
Transcription Factors
Quiz#7 LC710 10/18/10 name___________
Transcription.
Gene Regulation Section 12–5
Quiz #6 (8%) Biol710 11/19/12 name___________
Biotechnology and Genetic Engineering PBIO 4500/5500
Quiz#8 LC710 10/20/10 name___________
12-5 Gene Regulation.
Gel Retardation.
Quiz#4 LC710 11/14/11 name___________
Prokaryotic cells turn genes on and off by controlling transcription.
Recombinant DNA technology
Prokaryotic cells turn genes on and off by controlling transcription.
The Bare Lymphocyte Syndrome: Molecular Clues to the Transcriptional Regulation of Major Histocompatibility Complex Class II Genes  Angela DeSandro, Uma.
The Promoters of the Survival Motor Neuron Gene (SMN) and Its Copy (SMNc) Share Common Regulatory Elements  Andoni Echaniz-Laguna, Pierre Miniou, Deborah.
Schematic drawing of alternatively-spliced GFP reporter gene.
Prokaryotic (Bacterial) Gene Regulation
Proteins: Building Blocks of Life
Prokaryotic cells turn genes on and off by controlling transcription.
Prokaryotic cells turn genes on and off by controlling transcription.
Nuclear Localization and Transcriptional Repression Are Confined to Separable Domains in the Circadian Protein CRYPTOCHROME  Haisun Zhu, Francesca Conte,
Origins of replication and related regions of some representative theta-replicating plasmids from gram-negative bacteria. Origins of replication and related.
Gene Regulation A gene (DNA) is expressed when it is made into a functional product (protein/enzyme)
Prokaryotic cells turn genes on and off by controlling transcription.
PROTEIN-PROTEIN INTERACTIONS
Nuclear Localization and Transcriptional Repression Are Confined to Separable Domains in the Circadian Protein CRYPTOCHROME  Haisun Zhu, Francesca Conte,
Presentation transcript:

Quiz #7 (8%) Biol710 11/21/12 name___________ What biological process is being mimicked by current DNA sequencing technologies? (2%) _________________________________________________________________ Why do current DNA sequencing technologies only assign G, A, T, C to DNA sequences and not Cme, Ame, etc…? (2%) ________________________________________________________________ Q2 You are setting up a two plasmid system to identify an enhancer binding protein. One plasmid will assess binding, and the other will carry the expressed protein (cDNA). Where will you put enhancer sequence in the first plasmid below? Draw arrow. (1%) Is there a benefit to putting more than 1 site (1%)? _____________________________________________________________ What does the blue box represent in this experiment (1%)?___________________________ (be specific) minimal promoter (TATA box) The second plasmid will come from a cDNA library of potential DNA binding proteins. Be specific: How will you construct the second plasmid to ensure that this two plasmid system will identify the protein of interest (1%)