Clinical Trials to Real World:
Topics of Discussion
Two Key Questions
MARINA Trial: Mean Change in VA
ANCHOR Trial: Mean Change in VA
VIEW 1/2 Trial Results: Mean Change in BCVA From Baseline to Week 52
Monthly Injections: The Gold Standard of Treatment
LUMINOUS Study: Recruitment From Third Interim Analysis
LUMINOUS: VA Gains in Treatment-Naive Patients Stratified by Injection Frequency Over 1 Year
LUMINOUS: VA Stratified by Injection Frequency and Loading Dose
LUMINOUS: Safety Outcomes in Treatment-Naive Patients Over 1 Year
AURA Study: Summary of Mean Injections and VA Scores
AURA Study: Mean Change in VA Score From Baseline Over Time for All Patients by Country
LUMIERE Study: Changes in VA
UNCOVER Study: Medical Coverage Categories
UNCOVER: Frequency of Ranibizumab Injections/Year Were Lowest in Self-Paid Category
Real-World Considerations Contributing to Low Injection Frequency
Treat-and-Extend Regimen in Real-World Clinical Practice
Fight Retinal Blindness Study: 12-Month Outcomes
CATT 5-Year Study Results: Percent of Eyes With Fluid for 552 Eyes
FLUID Study: Design
FLUID Study: Summary
Importance of Qualitative Assessment on Monitoring
Concluding Remarks
Abbreviations