SAVE: Risk of total mortality associated with reduced kidney function GFR (mL/min/1.73m2) Multivariate adjusted risk ratio 95% CI >75 Ref 60-74 1.11 0.86-1.42 45-59 1.24 0.96-1.60 <45 1.81 1.32-2.48 p for trend 0.001 Tokmakova MP et al. Circulation 2004; available at http://circ.ahajournals.org
SAVE: Events prevented by captopril treatment in subjects with and without chronic kidney disease End point With CKD Without CKD CV events prevented per 100 subjects treated with captopril 12.4 5.5 Tokmakova MP et al. Circulation 2004; available at http://circ.ahajournals.org