Advances in Vasodilatory Shock:

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Presentation transcript:

Advances in Vasodilatory Shock:

Objectives

Defining Shock

Classification of Shock/Various Causes

Causes of Vasodilatory Shock

Final Common Pathway

What Happens in VS?

Hemodynamics in VS

Systems Involved In Restoring Effective Blood Pressure

Goals of Treatment For VS

Surviving Sepsis Campaign: Initial Resuscitation

Blood Lactate as a Predictor of Survival

Dynamic Fluid Assessment in Goal-Directed Therapy

Surviving Sepsis Campaign: Fluid Therapy

SAFE Trial: Albumin vs Saline Resuscitation

ALBIOS: Albumin Replacement in Patients With Severe Sepsis/Septic Shock

Gelatin vs Crystalloids and Albumin in Patients With Hypovolemia

Surviving Sepsis Campaign: Vasoactive Medications

Brief History of Vasopressors

Dopamine vs Norepinephrine for the Treatment of Critically Ill

Dopamine vs Norepinephrine for the Treatment of Septic Shock

Epinephrine vs Norepinephrine for the Treatment of Critically Ill

Vasopressin vs Norepinephrine for the Treatment of Septic Shock

Vasopressin vs Terlipressin for the Treatment of Vasodilatory Shock

Refractory Vasodilatory Shock and Angiotensin II

Angiotensin II Trials

ATHOS-3: Primary Outcome

ATHOS-3: Additional Endpoints

Angiotensin II: Current Status

V1a Agonist in Patients With Septic Shock

Still Evolving…

Take Home Points

Abbreviations

Abbreviations (cont)

Abbreviations (cont)

Abbreviations (cont)