Nat. Rev. Neurol. doi: /nrneurol

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Nat. Rev. Neurol. doi:10.1038/nrneurol.2017.96 Figure 3 Possible clinicopathological correlations for frontotemporal dementia syndromes Figure 3 | Possible clinicopathological correlations for frontotemporal dementia syndromes. The figure shows the pathologies associated with each frontotemporal dementia (FTD) syndrome. The three main frontotemporal lobar degeneration (FTLD) molecular pathologies — FTLD-tau, FTLD-TDP and FTLD-FUS — are represented in different shades of blue, and Alzheimer disease (AD) pathology is in yellow. The areas of crossover between syndromes and pathologies are qualitative rather than quantitative. The centre of the rhombus indicates the most frequent pathology for each syndrome. bvFTD, behavioural variant FTD; CBS, corticobasal syndrome; FTD–MND, FTD with motor neuron disease; FUS, fused in sarcoma; nfvPPA, nonfluent/agrammatic variant PPA; PPA, primary progressive aphasia; PSP-S, progressive supranuclear palsy syndrome; svPPA, semantic variant PPA; TDP-43, TAR DNA-binding protein 43. Elahi, F. M. & Miller, B. L. (2017) A clinicopathological approach to the diagnosis of dementia Nat. Rev. Neurol. doi:10.1038/nrneurol.2017.96