A powerful new agonist: flooding the system with growth hormone

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Presentation transcript:

A powerful new agonist: flooding the system with growth hormone Victoria S. Lim Kidney International Volume 77, Issue 5, Pages 385-387 (March 2010) DOI: 10.1038/ki.2009.487 Copyright © 2010 International Society of Nephrology Terms and Conditions

Figure 1 A diagram of GH–IGF-1 axis physiology. Solid lines indicate stimulatory effects; dotted lines indicate inhibitory effects. Xs represent steps along the axis where chronic kidney disease patients showed defective function. AKL-0707 is the new GH-releasing hormone super-agonist. GHRH, growth hormone–releasing hormone; IGF-1, insulin-like growth factor 1. Kidney International 2010 77, 385-387DOI: (10.1038/ki.2009.487) Copyright © 2010 International Society of Nephrology Terms and Conditions