Epilepsy: Contemporary Perspectives on Evaluation and Treatment

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Presentation transcript:

Epilepsy: Contemporary Perspectives on Evaluation and Treatment GREGORY D. CASCINO, M.D. Mayo Clinic Proceedings Volume 69, Issue 12, Pages 1199-1211 (December 1994) DOI: 10.1016/S0025-6196(12)65776-0 Copyright © 1994 Mayo Foundation for Medical Education and Research Terms and Conditions

Fig. 1 Extracranial interictal electroencephalogram of 37-year-old woman with partial epilepsy of left anterior temporal lobe origin, showing focal or anatomically restricted spike discharges. (Illustration courtesy of Dr. Frank W. Sharbrough, Department of Neurology, Mayo Clinic Rochester.) Mayo Clinic Proceedings 1994 69, 1199-1211DOI: (10.1016/S0025-6196(12)65776-0) Copyright © 1994 Mayo Foundation for Medical Education and Research Terms and Conditions

Fig. 2 Extracranial ictal electroencephalogram of 32-year-old man with generalized epilepsy during clinical nonconvulsive seizure, revealing generalized atypical spike and slow-wave complexes. (Illustration courtesy of Dr. Donald W. Klass, Division of Clinical Neurophysiology, Mayo Clinic Rochester.) Mayo Clinic Proceedings 1994 69, 1199-1211DOI: (10.1016/S0025-6196(12)65776-0) Copyright © 1994 Mayo Foundation for Medical Education and Research Terms and Conditions

Fig. 3 Magnetic resonance image of patient with intractable partial epilepsy, snowing intracranial mass in left posterior mesial temporal lobe (arrow). Grade I to II astrocytoma was subsequently resected. (Note: left cerebral hemisphere is on right side of photograph.) (From Fried I, Cascino GD. Lesional surgery. In: Engel J Jr, editor. Surgical Treatment of the Epilepsies. 2nd ed. New York: Raven Press, 1993: 501–509. By permission.) Mayo Clinic Proceedings 1994 69, 1199-1211DOI: (10.1016/S0025-6196(12)65776-0) Copyright © 1994 Mayo Foundation for Medical Education and Research Terms and Conditions

Fig. 4 Magnetic resonance image of patient with simple partial seizures consisting of sensory symptoms in left arm, revealing neuronal migration abnormality in right frontal lobe. (Note: right cerebral hemisphere is on left side of photograph.) IP = inferoposterior. Mayo Clinic Proceedings 1994 69, 1199-1211DOI: (10.1016/S0025-6196(12)65776-0) Copyright © 1994 Mayo Foundation for Medical Education and Research Terms and Conditions

Fig. 5 Magnetic resonance image after injection of gadolinium and diethylenetriamine pentaacetic acid, revealing arteriovenous malformation in left posterior temporal lobe (arrow). (Note: left temporal lobe is on right side of photograph.) Mayo Clinic Proceedings 1994 69, 1199-1211DOI: (10.1016/S0025-6196(12)65776-0) Copyright © 1994 Mayo Foundation for Medical Education and Research Terms and Conditions

Fig. 6 Magnetic resonance images, showing agenesis of corpus callosum. A, Coronal reconstruction. B, Sagittal reconstruction. Mayo Clinic Proceedings 1994 69, 1199-1211DOI: (10.1016/S0025-6196(12)65776-0) Copyright © 1994 Mayo Foundation for Medical Education and Research Terms and Conditions

Fig. 7 Magnetic resonance image in oblique-coronal plane of patient with mesial temporal sclerosis, revealing atrophy of left hippocampal formation (arrow). Hippocampal volume loss was confirmed with quantitative magnetic resonance image analysis. (Note: left hippocampus is on right side of photograph.) IP = inferoposterior. Mayo Clinic Proceedings 1994 69, 1199-1211DOI: (10.1016/S0025-6196(12)65776-0) Copyright © 1994 Mayo Foundation for Medical Education and Research Terms and Conditions