From the 2015 Conferences to the Clinic

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Presentation transcript:

From the 2015 Conferences to the Clinic

Program Goals

A Double-Blind, Randomized, Placebo-Controlled, Flexible-Dose Study of Vilazodone in Patients With GAD

Vilazodone-GAD Randomized Controlled Trial Results Efficacy

Vilazodone-GAD Randomized Controlled Trial Improvement in Functional Domains

From the 2015 Conferences to the Clinic

Post hoc Analyses of Suicidality in Clinical Trials of Vilazodone

Suicidality in Vilazodone Clinical Trials

Levomilnacipran ER Treatment in Adult Patients With First-Episode, Highly Recurrent, and Chronic MDD

Levomilnacipran ER

Efficacy of Vortioxetine in the Treatment of Patients With MDD in Short-term Placebo-Controlled Studies: A Meta-analysis of 11 Studies

Efficacy of Vortioxetine Results

From the 2015 Conferences to the Clinic

Lurasidone for the Treatment of MDD With Mixed Features A Randomized, Double-Blind, Placebo-Controlled, 6-Wk Trial

Lurasidone for the Treatment of MDD With Mixed Features A Randomized, Double-Blind, Placebo-Controlled, 6-Wk Trial (cont)

Patterns of Antidepressant Efficacy With Quetiapine ER as Adjunct to Different Ongoing Antidepressants: Exploration of MOA Hypotheses

Patterns of Antidepressant Efficacy With Quetiapine ER as Adjunct to Different Ongoing Antidepressants: Exploration of MOA Hypotheses (cont)

Efficacy and Safety of Cariprazine as Adjunctive Therapy in MDD A Double-Blind, Randomized, Placebo-Controlled Study

From the 2015 Conferences to the Clinic

Metabolic Tolerability Profile of Adjunct Brexpiprazole (OPC-34712) in MDD Study Design

Metabolic Tolerability Profile Results

Metabolic Tolerability Profile Results (cont)

Efficacy and Safety of Brexpiprazole (OPC-34712) as Adjunctive Treatment in MDD Pooled Analysis of 2 Pivotal Studies

Efficacy and Safety of Brexpiprazole Results

Abbreviations

Abbreviations (cont)

References

References (cont)

References (cont)