Placental Mechanics in the Zika-Microcephaly Relationship

Slides:

Advertisements

Similar presentations

Individualized Medicine from Prewomb to Tomb Eric J. Topol Cell Volume 157, Issue 1, Pages (March 2014) DOI: /j.cell Copyright.

Advertisements

What We Talk About When We Talk About Fat Evan D. Rosen, Bruce M. Spiegelman Cell Volume 156, Issue 1, Pages (January 2014) DOI: /j.cell

Maintaining Cell Identity through Global Control of Genomic Organization Gioacchino Natoli Immunity Volume 33, Issue 1, Pages (July 2010) DOI: /j.immuni

Human Gut Microbes Use Multiple Transporters to Distinguish Vitamin B12 Analogs and Compete in the Gut Patrick H. Degnan, Natasha A. Barry, Kenny C. Mok,

Distribution of Human Embryonic Stem Cell Lines: Who, When, and Where Jennifer B. McCormick, Jason Owen-Smith, Christopher Thomas Scott Cell Stem Cell.

An Essential Role for the NLRP3 Inflammasome in Host Defense against the Human Fungal Pathogen Candida albicans Amy G. Hise, Jeffrey Tomalka, Sandhya Ganesan,

Nucleocapsid Phosphorylation and RNA Helicase DDX1 Recruitment Enables Coronavirus Transition from Discontinuous to Continuous Transcription Chia-Hsin.

Genes Induced Late in Infection Increase Fitness of Vibrio cholerae after Release into the Environment Stefan Schild, Rita Tamayo, Eric J. Nelson, Firdausi.

Human Brown Adipose Tissue Sven Enerbäck Cell Metabolism Volume 11, Issue 4, Pages (April 2010) DOI: /j.cmet Copyright © 2010.

A View to a Kill: The Bacterial Type VI Secretion System Brian T. Ho, Tao G. Dong, John J. Mekalanos Cell Host & Microbe Volume 15, Issue 1, Pages 9-21.

Cell-to-Cell Transfer of M. tuberculosis Antigens Optimizes CD4 T Cell Priming Smita Srivastava, Joel D. Ernst Cell Host & Microbe Volume 15, Issue 6,

Merkel Cell Polyomavirus Small T Antigen Controls Viral Replication and Oncoprotein Expression by Targeting the Cellular Ubiquitin Ligase SCFFbw7 Hyun.

Mechanisms of Age-Related Macular Degeneration Jayakrishna Ambati, Benjamin J. Fowler Neuron Volume 75, Issue 1, Pages (July 2012) DOI: /j.neuron

H. pylori GPS: Modulating Host Metabolites for Location Sensing

Interferons Coordinate a Multifaceted Defense

Trained Immunity: An Ancient Way of Remembering

P Bodies, Stress Granules, and Viral Life Cycles

Diabetes Risk Begins In Utero

Influenza A Virus Lures Autophagic Protein LC3 to Budding Sites

The Avian Influenza Virus Polymerase Brings ANP32A Home to Roost

Volume 9, Issue 2, Pages (August 2011)

P Bodies, Stress Granules, and Viral Life Cycles

Balance of Power in Host-Virus Arms Races

The Distinct Roles of JAM-A in Reovirus Pathogenesis

Niv Zmora, David Zeevi, Tal Korem, Eran Segal, Eran Elinav

Nandan S. Gokhale, Stacy M. Horner Cell Host & Microbe

Volume 20, Issue 4, Pages (October 2016)

Warfare between Host Immunity and Bacterial Weapons

Unsweetened IgG Is Bad for Dengue Patients

Arturo Casadevall, Liise-anne Pirofski Cell Host & Microbe

The Distinct Roles of JAM-A in Reovirus Pathogenesis

Portrait of a Killer: Genome of the 2014 EBOV Outbreak Strain

Shigella Targets T Cells

Octavio Ramilo, Asunción Mejías Cell Host & Microbe

Clarification of INTERGROWTH-21st newborn birthweight standards

Microbial Vertical Transmission during Human Pregnancy

Metformin Joins Forces with Microbes

Autophagy, Apoptosis, and the Influenza Virus M2 Protein

A Microbiome Foundation for the Study of Crohn’s Disease

Neutrophils Cause an Intravascular Traffic Jam

Gambling with Flu: “All in” to Maximize Reward

Type VI Secretion: Not Just for Pathogenesis Anymore

Placental Malaria: From Infection to Malfunction

Neural-Immune Communication in Caenorhabditis elegans

At the Intersection of Plant Growth and Immunity

Arturo Casadevall, Liise-anne Pirofski Cell Host & Microbe

The Avian Influenza Virus Polymerase Brings ANP32A Home to Roost

Restriction of Zika Virus by Host Innate Immunity

Finding Leishmania: A Deadly Game of Hide-and-Seek

Breaking the Barrier: Host Cell Invasion by Lujo Virus

Proteins in Plant Brassinosteroid Signaling

Recognizing Macrophage Activation and Host Defense

Caging Targets for Destruction

Zika Virus: Two or Three Lineages?

Gut Microbes Take Their Vitamins

A Microbiome Foundation for the Study of Crohn’s Disease

The Yeast Saccharomyces cerevisiae: A Versatile Model System for the Identification and Characterization of Bacterial Virulence Proteins Keri A. Siggers,

Shigella Navigates Tight Corners

Staphylococcus aureus Osteomyelitis: Bad to the Bone

For HIV, It's Never Too Late to Grow Up

Wilbert Bitter, Coen Kuijl Cell Host & Microbe

Viral Suppressors of RNA-Based Viral Immunity: Host Targets

Understanding How Hepatitis C Virus Builds Its Unctuous Home

A Host MicroRNA Brokers Truce with HSV-1

Pneumococcus Adapts to the Sickle Cell Host

David Hubel and Torsten Wiesel

HIV and Chemokine Binding to Red Blood Cells—DARC Matters

Don’t Bite the Hand that Feeds You

West African Ebola Virus Strains: Unstable and Ready to Invade?

Time Heals All Wounds … But Wounds Heal Faster with Lactobacillus

Presentation transcript:

Placental Mechanics in the Zika-Microcephaly Relationship Jennifer J. Adibi, Yaqi Zhao, Abigail R. Cartus, Phalguni Gupta, Lance A. Davidson Cell Host & Microbe Volume 20, Issue 1, Pages 9-11 (July 2016) DOI: 10.1016/j.chom.2016.06.013 Copyright © 2016 Elsevier Inc. Terms and Conditions

Figure 1 Zika Virus Has to Navigate Several Cell Layers and Tissue Barriers in Order to Access the Embryo/Fetus in the First Trimester of Pregnancy (A) Gestational sac before the onset of maternal-placental blood flow (<10 weeks gestation). Figure from Adibi et al. (2016). Lancet 387, 1587–1590 (illustrator Adrian Roots). (B) The architecture and cellular layers of the placental villous and chorion. Figure from Robbins et al. (2010). PLoS Pathog. 6, e1000732. Cell Host & Microbe 2016 20, 9-11DOI: (10.1016/j.chom.2016.06.013) Copyright © 2016 Elsevier Inc. Terms and Conditions