Serum cytotoxic T lymphocyte–associated antigen 4 in Hymenoptera venom allergy and its modulation by specific immunotherapy Daniele Saverino, BS, Anna.

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Presentation transcript:

Serum cytotoxic T lymphocyte–associated antigen 4 in Hymenoptera venom allergy and its modulation by specific immunotherapy Daniele Saverino, BS, Anna Maria Riccio, BS, Anthi Rogkakou, MD, Marcello Bagnasco, MD, Patrizia Bonadonna, MD, Rita Simone, BS, Alessandra Chiappori, BS, Cinzia Gamalero, BS, Giovanni Passalacqua, MD, Giorgio Walter Canonica, MD, Giampaola Pesce, BS Journal of Allergy and Clinical Immunology Volume 123, Issue 1, Pages 258-260 (January 2009) DOI: 10.1016/j.jaci.2008.09.023 Copyright © 2009 American Academy of Allergy, Asthma & Immunology Terms and Conditions

Fig 1 Upper panel: Left, Serum CTLA-4 values before and after immunotherapy induction in patients with HVA, healthy subjects (H), and patients with respiratory allergy (RA). Right, Serum IL-10 values before and after immunotherapy. Middle panel: Specific IgG4 (right) and IgE (left) values before and after immunotherapy. Medians are shown as horizontal thick bars. Lower panel: Western blot of selected sera. Lanes A through C, Patients with HVA (nos. 7, 14, and 22) before SIT; lanes G through I, the same patients after SIT; lanes D and E, patients with respiratory allergy; lane F, healthy subject. Journal of Allergy and Clinical Immunology 2009 123, 258-260DOI: (10.1016/j.jaci.2008.09.023) Copyright © 2009 American Academy of Allergy, Asthma & Immunology Terms and Conditions