Volume 147, Issue 1, (September 2011) Cancer's Epigenome    Cell  Volume 147, Issue 1, (September 2011) DOI: 10.1016/j.cell.2011.09.021 Copyright © 2011 Terms and Conditions

A multidimensional scaling of methylation for selected CpGs in cancer, showing the distribution of normal tissues (left) and cancer (right). A few cancer samples fall within the normal range but do not define a tight distribution themselves. Dotted lines indicate the typical variation for normal tissues. Image courtesy of K.D. Hansen and W. Timp. Cell 2011 147, DOI: (10.1016/j.cell.2011.09.021) Copyright © 2011 Terms and Conditions

Genome-wide visualization of somatic mutation targets in non-Hodgkin lymphoma from Morin et al. (2011). Purple circles mark genes mutated in more than one case, with their diameters proportional to the number of cases with single-nucleotide variants observed. Image courtesy of R. Morin. Cell 2011 147, DOI: (10.1016/j.cell.2011.09.021) Copyright © 2011 Terms and Conditions

Histology image of a hepatitis C-associated liver cancer case with an ARID2 mutation. Image courtesy of M. Torbenson. Cell 2011 147, DOI: (10.1016/j.cell.2011.09.021) Copyright © 2011 Terms and Conditions

The confocal image in the Sputnik satellite shows a cell overexpressing satellite DNA and with abnormally amplified centrosomes (red). At center is a mathematical deconvolution of the confocal image to resolve the tubulin fibers (green) and the individual chromosomes (blue). Image courtesy of Q. Zhu, J. Fitzpatrick, and J. Simon. Cell 2011 147, DOI: (10.1016/j.cell.2011.09.021) Copyright © 2011 Terms and Conditions