Agenda 7:30pm Welcome M. Everitt/R. Chinnock/J. Alejos 7:40pm Steering Committee Update Melanie Everitt 7:45pm DCC Update James Kirklin 8:00pm Database Committee Report Marc Richmond 8:15pm Foundation Update Craig Collum 8:30pm DISCUSSION Research Project Timeline of Submission Progression of Elections 8:55pm Pedimacs Update Betsy Blume 9:10pm Scientific Committee Report Anne Dipchand 9:20pm New Officers and New Business 9:30pm Adjourn

Database Committee Report Committee Members Marc Richmond, MD, MS Chair Nancy McDonald, CPNP Non Physician Rep. Heather Tinling, RN, BSN Non Physician Rep. Jacqueline Lamour, MD Member at Large Philip Thrush, MD Member at Large Joshua Sparks, MD Member at Large Katie Simpson, MD Member at Large James Kirklin, MD DCC Rep.

Database Committee Report Infection Organism Mapping Infection organisms have been a free text field since data collection began in 1993 Hundreds of unique variations of organisms have been entered Committee reviewed and mapped all organisms to a series of check boxes to make data more ‘useable’ for research and analysis Removed infection ‘type’ to prevent data entry errors

Database Committee Report Current Infection Organism Data Collection

Database Committee Report Infection Definition Previous Definition: Evidence of infectious process requiring IV therapy or life threatening requiring oral therapy. New Definition: Is this infection a severe infection that requires IV therapy, hospitalization for infection >2 days, or escalation of care in an already hospitalized patient?

Database Committee Report Annual Follow-up Medication Mapping Annual Follow-up medications have been a free text field since data collection began in 1993 Thousands of unique variations of medications and spellings have been entered Committee reviewed and mapped all medications to a series of check boxes to make data more ‘useable’ for research and analysis Mapping is under final review by the committee and will be implemented in the electronic system soon.

Database Committee Report Annual Follow-up Medication Mapping Medications will also carry over from previous follow-up for coordinator to review and confirm form to reduce data entry burden of entering medications again each year. A ‘Medication Look Up Table’ will be added to the manual showing what was mapped to each category for coordinators to reference and reduce the data entered into ‘other, specify’.

Database Committee Report New Medication Categories Anti-hypertensive Mycophenolate (Cellcept, Myfortic) Azathioprine (Imuran) Pneumocystis Prophylaxis Cytoxan (Cyclophosphamide) Prednisone Cyclosporine Sirolimus (Rapamycin) Diuretic Statin Everolimus Tacrolimus (Prograf, FK506) Immune globulin Other, specify Methotrexate

Database Committee Report Clinical Trial Tracking TEAMMATE Trial beginning December 1st All patients enrolled in the TEAMMATE trial should have their study ID number entered into the PHTS database. This will allow patients enrolled in the trial to be followed long term after the trial has ended. Available in release 1.1.4 of the web based data entry system.

Database Committee Report Clinical Trial Tracking Web Based Data Entry System

Database Committee Report Clinical Trial Tracking Web Based Data Entry System

Database Committee Report Action Items Carrying Over to New Committee Listing/Transplant/Follow-up/Dialysis Forms Range checks for all lab values Additional data entry fields for units used at centers outside of the US Ranges checks for hemodynamics fields Infection Form Mapping Free Text entries into ‘significant long term sequelae’ Free Text entries into Surgical Intervention Post Tx Annual F/up Mapping Free Text entries into ‘additional events’ Manual Overhaul Spring Coordinator Webinar