Pediatric Antiepileptic Treatment Strategies

Introduction

Factors Influencing Treatment Choice

Patient Case: Jack

Patient Case: Jack (cont)

Patient Case: Jack (cont)

Correct Diagnosis and Treatment Approach?

Could It Be Benign Focal Epilepsy?

Factors to Be Considered Early On

Patient Case: Jack (cont)

Possible Reasons for Breakthrough Seizures

Other Approaches With the Second AED?

Use of Watchful Waiting and Imaging

Patient Case: Jack (cont)

Potential Reasons for Seizures

Adherence Rates in a Scottish Population Cohort

Discussing Adherence With Parents

Definitive Diagnosis? Where to Go From Here

Definitive Diagnosis? Where to Go From Here (cont)

Drug-Resistant Epilepsy: ILAE Definition

Drug-Resistant Epilepsy: Considerations

Effect of Early Seizures on Outcome

NICE Guidelines: Highlights From General Information on Pharmacologic Treatment

ILAE Summary Level of Evidence by Seizure Type for Pharmacologic Treatment

Paucity of Data on AEDs in Childhood Epilepsy

MHRA Safety Update in the United Kingdom: Risk-Based Categories for Switching Products

Patient Case: Jack (cont)

Neuropsychological and Neurobehavioral Development

NICE: Specialist Referral

Ketogenic Diet

Patient Case: Next Steps

Concluding Remarks

Abbreviations