Control SC236(5mM) SC236(5mM) SC236(25mM) SC236(25mM)

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Control SC236(5mM) SC236(5mM) SC236(25mM) SC236(25mM) +PGE2(1mM) BrdU Incorporation (Absorbance) p<0.05 ns p<0.01 +PGE2(1mM) Supplementary Figure 1. The effect of cycloxygenase-2 inhibition on HCA7 cell proliferation. The results show the extent of BrdU incorporation (absorbance, y-axis) in HCA7 cells following treatment for 24 hours under the conditions outlined on the x-axis. The results reflect the mean +/- standard error for n=3. One way ANOVA suggested a significant effect of treatment (p=0.0001). The differences between groups was then assessed by the bonferroni multiple comparisons test; p values are as shown.