Volume 119, Issue 5, Pages (November 2000)

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Volume 119, Issue 5, Pages 1191-1202 (November 2000) Primary gastric B-Cell lymphoma: Results of a prospective multicenter study Wolfgang Fischbach, Brigitte Dragosics, Maria–Elisabeth Kolve–Goebeler, Christian Ohmann, Axel Greiner, Qin Yang, Stephan Böhm, Patrick Verreet, Olaf Horstmann, Martin Busch, Eckhart Dühmke, Hans–Konrad Müller–Hermelink, Klaus Wilms Gastroenterology Volume 119, Issue 5, Pages 1191-1202 (November 2000) DOI: 10.1053/gast.2000.19579 Copyright © 2000 American Gastroenterological Association Terms and Conditions

Fig. 1 Study population. hgNHL, high-grade non-Hodgkin's lymphoma; Hp, H. pylori. *Nonresponder to H. pylori–eradication therapy. Gastroenterology 2000 119, 1191-1202DOI: (10.1053/gast.2000.19579) Copyright © 2000 American Gastroenterological Association Terms and Conditions

Fig. 2 Treatment groups in low-grade non-Hodgkin's gastric lymphoma. CS, clinical stage; PS, pathohistologic stage; risk, tumor size > 5 cm, multifocal growth, tumor penetrating the serosa; R0, complete tumor resection; R1, microscopic tumor residuals; R2, macroscopic tumor residuals; Hp, H. pylori; RTx, radiotherapy (30 Gy total abdominal irradiation + 10 Gy or 16 Gy involved field in R0- and R1/R2-resected patients, respectively); L1, L2, L3, treatment groups for intention-to-treat analysis. Gastroenterology 2000 119, 1191-1202DOI: (10.1053/gast.2000.19579) Copyright © 2000 American Gastroenterological Association Terms and Conditions

Fig. 3 Treatment groups in high-grade non-Hodgkin's gastric lymphoma. CS, clinical stage; PS, pathohistologic stage; R0, complete tumor resection; R1, microscopic tumor residuals; R2, macroscopic tumor residuals; CTx, chemotherapy (6× CHOP); RTx, radiotherapy (40 Gy involved field); H1, H2, H3, treatment groups for intention-to-treat analysis. Gastroenterology 2000 119, 1191-1202DOI: (10.1053/gast.2000.19579) Copyright © 2000 American Gastroenterological Association Terms and Conditions

Fig. 4 (A) Intention-to-treat analysis of low-grade gastric lymphoma. P > 0.05 (log rank test). L1: EI, H. pylori–positive, eradication therapy. L2: EI1, EI2 without risk, R0 resection (including H. pylori–negative, nonresponder to eradication). L3: EI2 with risk, EII, R0 resection; EI/II, R1/R2 resection. (B) Intention-to-treat analysis of high-grade gastric lymphoma. P < 0.001 (log rank test), H3 vs. H1/H2. H1: EI, R0/R1 resection. H2: EII, R0/R1 resection. H3: EI/II, R2 resection or no surgery/exploratory laparotomy. Gastroenterology 2000 119, 1191-1202DOI: (10.1053/gast.2000.19579) Copyright © 2000 American Gastroenterological Association Terms and Conditions