Whole genome sequencing of Mycobacterium tuberculosis for detection of drug resistance: a systematic review  D. Papaventsis, N. Casali, I. Kontsevaya,

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Whole genome sequencing of Mycobacterium tuberculosis for detection of drug resistance: a systematic review  D. Papaventsis, N. Casali, I. Kontsevaya, F. Drobniewski, D.M. Cirillo, V. Nikolayevskyy  Clinical Microbiology and Infection  Volume 23, Issue 2, Pages 61-68 (February 2017) DOI: 10.1016/j.cmi.2016.09.008 Copyright © 2016 Terms and Conditions

Fig. 1 PRISMA study selection flow diagram. Clinical Microbiology and Infection 2017 23, 61-68DOI: (10.1016/j.cmi.2016.09.008) Copyright © 2016 Terms and Conditions

Fig. 2 Methodological quality assessment of selected studies using QUADAS-2 tool. (a) Risk of bias and (b) applicability. Clinical Microbiology and Infection 2017 23, 61-68DOI: (10.1016/j.cmi.2016.09.008) Copyright © 2016 Terms and Conditions

Fig. 3 Forest plot of studies evaluating (a) sensitivity and (b) specificity of whole genome sequencing for detection of resistance to rifampicin. Clinical Microbiology and Infection 2017 23, 61-68DOI: (10.1016/j.cmi.2016.09.008) Copyright © 2016 Terms and Conditions

Fig. 4 Forest plot of studies evaluating (a) sensitivity and (b) specificity of whole genome sequencing for detection of resistance to isoniazid. Clinical Microbiology and Infection 2017 23, 61-68DOI: (10.1016/j.cmi.2016.09.008) Copyright © 2016 Terms and Conditions