COXIELLA BURNETTI INFECTION AS POSSIBLE CAUSE OF PANUVEITIS Sofía Ajamil Rodanés JM Herreras Cantalapiedra Hospital Clínico Universitario Valladolid

INTRODUCTION CASE REPORT ♀ Coxiella Burnetti - intracellular organism - transmitted though inhalation of infected aerosols - ophthalmic manifestiations are rare We describe the case of a woman who presented with bilateral panuveitis in the context of coxiella infection. CASE REPORT ♀ 22 year-old swine farmer presented with a five month history of loss of vision in her LE BCVA 20/20 in right eye(RE) and 20/40 in the left eye(LE) Funduscopy: vitritis, macular oedema and vasculitis in both eyes

C All results were negative except for positive IgM titers for Coxiella Burnetti. The patient was treated with doxycycline 100mg every 12 hours for 3 weeks. One year later the patient was stable withtopical prednisolone and nepafenac.

6 months later Loss of vision, vitreous opacities, focus of retinitis LE and retinal vasculitis along the temporal vessels Macular edema in both eyes

Treatment with infliximab 5mg/kg/day was started Treatment: AZATHIOPRINE 50MG A DAY + PREDNISOLONE 20MG A DAY After 9 months without response the visual acuity dropped to RE 20/40 LE 20/200  Treatment with infliximab 5mg/kg/day was started CONCLUSIONS C. burnetti should be added to the list of pathogens responsible of intraocular inflammation by an infective and/or inmmune mechanism.