What Impacts the All Cause Risk of Reoperation after Pelvic Organ Prolapse Repair? A Comparison of Mesh and Native Tissue Approaches in 110,329 Women 

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What Impacts the All Cause Risk of Reoperation after Pelvic Organ Prolapse Repair? A Comparison of Mesh and Native Tissue Approaches in 110,329 Women  Kai B. Dallas, Lisa Rogo-Gupta, Christopher S. Elliott  The Journal of Urology  Volume 200, Issue 2, Pages 389-396 (August 2018) DOI: 10.1016/j.juro.2018.02.3093 Copyright © 2018 American Urological Association Education and Research, Inc. Terms and Conditions

Figure 1 Independent effects of incontinence procedure and mesh use for POP repair on mesh complication repeat surgery rates. Concomitant incontinence procedure increased incidence of additional surgery for mesh complications by similar 0.7% to 0.8% rate regardless of mesh for POP repair. Similarly mesh for POP repair increased incidence of additional surgery for mesh complications by 1.5% to 1.6% regardless of incontinence procedure. We hypothesized that 0.7% repeat surgery rate for mesh complication in no mesh, no incontinence surgery group was due to likelihood that some patients underwent mesh surgery prior to study period. The Journal of Urology 2018 200, 389-396DOI: (10.1016/j.juro.2018.02.3093) Copyright © 2018 American Urological Association Education and Research, Inc. Terms and Conditions

Figure 2 Best repair outcomes (blue curves) and 99% CI (gray curves). For anterior repairs approximately 5% overall mesh rate provided best outcome (a). Sensitivity analysis of anterior compartment only repairs revealed similar findings. For anterior and apical combined repairs approximately 10% mesh rate provided best outcome (b). Sensitivity analysis of anterior and apical compartment only repairs revealed similar findings. The Journal of Urology 2018 200, 389-396DOI: (10.1016/j.juro.2018.02.3093) Copyright © 2018 American Urological Association Education and Research, Inc. Terms and Conditions